SCHEMBL1711524

SCHEMBL1711524

CN[C@H](C(=O)N[C@@H](CCCNC(N)=O)C(=O)O)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ C3AR1 Q16581 1/20 0.44
▸ CTDSP1 Q9GZU7 1/20 0.39
▸ NOD1 Q9Y239 3/20 0.39
▸ FOLH1 Q04609 2/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ FURIN P09958 5/20 0.38
▸ SHMT1 P34896 1/20 0.38
▸ GNPAT O15228 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KLK7 P49862 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ECE1 P42892 2/20 0.37
▸ POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711520 1.00 C3AR1 (0.44) C3AR1CTDSP1NOD1FOLH1SMN1; SMN2
SCHEMBL23393940 0.90 SIRT5 (0.39) C3AR1NOD1SMN1; SMN2FURINKMT2A
SCHEMBL22045351 0.89 FURIN (0.39) C3AR1SMN1; SMN2FURIN
SCHEMBL29977834 0.89 NPY4R (0.39) NOD1FOLH1SMN1; SMN2FURINGNPAT
SCHEMBL21915057 0.89 C3AR1 (0.34) C3AR1CTDSP1SMN1; SMN2FURINKMT2A
SCHEMBL23736705 0.89 FURIN (0.36) C3AR1SMN1; SMN2FURINKMT2APOLB
SCHEMBL21103418 0.89 SIRT5 (0.36) C3AR1NOD1SMN1; SMN2FURINKMT2A
SCHEMBL20795891 0.89 FURIN (0.36) C3AR1SMN1; SMN2FURINKMT2APOLB
SCHEMBL20159819 0.89 FURIN (0.36) C3AR1SMN1; SMN2FURINKMT2APOLB
SCHEMBL24490420 0.89 C3AR1 (0.34) C3AR1CTDSP1SMN1; SMN2FURINKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024140917-A1 ANTI-CD40 ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 上海盛迪医药有限公司 2024-07-04 — — WO claimed
EP-4289857-A1 DRUG CONJUGATE OF GLUCOCORTICOID RECEPTOR AGONIST, AND APPLICATION THEREOF IN MEDICINE Shanghai Senhui Medicine Co., Ltd. (CN) 2023-12-13 — — EP claimed
CN-116761820-A Pharmaceutical conjugates of glucocorticoid receptor agonists and their use in medicine 上海森辉医药有限公司 2023-09-15 — — CN claimed
US-11560422-B2 Sulfonamide-containing linkage systems for drug conjugates ZYMEWORKS INC. 2023-01-24 — — US claimed
WO-2022166779-A1 DRUG CONJUGATE OF GLUCOCORTICOID RECEPTOR AGONIST, AND APPLICATION THEREOF IN MEDICINE 上海森辉医药有限公司 2022-08-11 — — WO claimed
US-20260146088-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2026-05-28 — — US disclosed
EP-4703388-A1 ANTI-TF ANTIBODY AND ANTI-TF ANTIBODY-DRUG CONJUGATE AND MEDICAL USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-03-04 — — EP disclosed
US-20260028420-A1 ANTI-TUMOR ANTIBODIES IMMUNOME INC (US) 2026-01-29 — — US disclosed
US-20260022193-A1 METHODS OF TREATMENT USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 ZYMEWORKS BC INC (CA) 2026-01-22 — — US disclosed
EP-4674437-A1 ANTI-DLL3 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND PHARMACEUTICAL USE THEREOF Suzhou Suncadia Biopharmaceuticals Co., Ltd. (CN) 2026-01-07 — — EP disclosed
US-12435157-B2 Methods of using a bispecific antigen-binding construct targeting HER2 for the treatment of biliary tract cancers ZYMEWORKS BC INC. (CA) 2025-10-07 — — US disclosed
US-20250276077-A1 EPHA2 ANTIBODIES IMMUNOME INC (US) 2025-09-04 — — US disclosed
EP-2344478-A2 NOVEL CC-1065 ANALOGS AND THEIR CONJUGATES Syntarga B.V. (NL) 2011-07-20 — — EP disclosed
US-20110065767-A1 Substituted CC-1065 Analogs and Their Conjugates SYNTARGA B.V. (NL) 2011-03-17 — — US disclosed
WO-2010062171-A2 NOVEL CC-1065 ANALOGS AND THEIR CONJUGATES SYNTARGA B.V. (NL) 2010-06-03 — — WO disclosed
EP-2173739-A1 SUBSTITUTED CC-1065 ANALOGS AND THEIR CONJUGATES Syntarga B.V. (NL) 2010-04-14 — — EP disclosed
US-20090318668-A1 Water-Soluble CC-1065 Analogs and Their Conjugates Georg-August-Universität Göttingen Stiftung öffentlichen Rechts (ohne Bereich Humanmedizin) (DE) 2009-12-24 — — US disclosed
WO-2009017394-A1 SUBSTITUTED CC-1065 ANALOGS AND THEIR CONJUGATES SYNTARGA B.V. (NL) 2009-02-05 — — WO disclosed
EP-1994000-A2 WATER-SOLUBLE CC-1065 ANALOGS AND THEIR CONJUGATES Syntarga B.V. (NL) 2008-11-26 — — EP disclosed
WO-2007089149-A2 WATER-SOLUBLE CC-1065 ANALOGS AND THEIR CONJUGATES SYNTARGA B.V. (NL) 2007-08-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090318668-A1 Water-Soluble CC-1065 Analogs and Their Conjugates PCNA, DCK, BAD C3AR1 933/4885CTDSP1 54/4885NOD1 3209/4885
US-20250276077-A1 EPHA2 ANTIBODIES EPHA2, EPHB2, EPHA1 C3AR1 56/4885CTDSP1 3603/4885NOD1 2822/4885
US-20260146088-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE H1-10, IGSF11, CD99 C3AR1 985/4885CTDSP1 3604/4885NOD1 4521/4885
US-20260022193-A1 METHODS OF TREATMENT USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 IGSF11, ERBB2, PDCD1LG2 C3AR1 1977/4885CTDSP1 721/4885NOD1 3684/4885
US-12435157-B2 Methods of using a bispecific antigen-binding construct targeting HER2 for the treatment of biliary tract cancers AURKC, AURKB, BSG C3AR1 1264/4885CTDSP1 2339/4885NOD1 2952/4885
US-20260028420-A1 ANTI-TUMOR ANTIBODIES B4GALT1, ST6GAL1, GALNT3 C3AR1 1473/4885CTDSP1 4189/4885NOD1 1878/4885
US-11560422-B2 Sulfonamide-containing linkage systems for drug conjugates MPST, TPST2, SULT1A1 C3AR1 4306/4885CTDSP1 1714/4885NOD1 3558/4885
US-20110065767-A1 Substituted CC-1065 Analogs and Their Conjugates PCNA, TOP1, TOP2B C3AR1 452/4885CTDSP1 359/4885NOD1 4345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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