SCHEMBL19605700

SCHEMBL19605700

CCOCC#CC#Cc1ccc(C(NC)C(F)(F)F)cc1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600911 0.91 ACACB (0.33) ACACB
SCHEMBL19606410 0.89 ACACB (0.31) ACACB
SCHEMBL24783334 0.82 HTR2A (0.32) ACACB
SCHEMBL18551308 0.81 ACACB (0.40) ACACB
SCHEMBL26748745 0.75 ACACB (0.39) ACACB
SCHEMBL19977461 0.75 ACACB (0.39) ACACB
SCHEMBL25059246 0.70 ACACB (0.34) ACACB
SCHEMBL18551220 0.69 ACACB (0.34) ACACB
SCHEMBL19606404 0.66 SLC2A1 (0.32) ACACB
SCHEMBL21214847 0.66 GRM5 (0.34) ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017197046-A1 C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 — — WO disclosed
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