SCHEMBL19606410

SCHEMBL19606410

CCNC(c1ccc(C#CC#CCOCC)cc1)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19605700 0.89 ACACB (0.31) ACACB
SCHEMBL19600911 0.79 ACACB (0.33) ACACB
SCHEMBL19606404 0.77 SLC2A1 (0.32) ACACB
SCHEMBL18551308 0.75 ACACB (0.40) ACACB
SCHEMBL19977461 0.74 ACACB (0.39) ACACB
SCHEMBL26748745 0.74 ACACB (0.39) ACACB
SCHEMBL24312112 0.72 CTSL (0.46) —
SCHEMBL24783334 0.72 HTR2A (0.32) ACACB
SCHEMBL24437180 0.67 PRCP (0.43) —
SCHEMBL24312242 0.67 PDE2A (0.42) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017197051-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2017-11-16 — — WO disclosed
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