Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24783334 | 0.91 | HTR2A (0.32) | ACACB | |
| SCHEMBL19605700 | 0.91 | ACACB (0.31) | ACACB | |
| SCHEMBL19606410 | 0.79 | ACACB (0.31) | ACACB | |
| SCHEMBL19606404 | 0.74 | SLC2A1 (0.32) | ACACB | |
| SCHEMBL20324201 | 0.71 | ACACB (0.39) | ACACB | |
| SCHEMBL18551308 | 0.70 | ACACB (0.40) | ACACB | |
| SCHEMBL9209153 | 0.69 | KCNH2 (0.41) | ACACBKCNH2MMP2MMP12 | |
| SCHEMBL5243364 | 0.68 | NPSR1 (0.53) | KCNH2MMP2MMP12 | |
| SCHEMBL10279764 | 0.67 | CTSL (0.41) | ACACBKCNH2CTSLCTSBCTSS | |
| SCHEMBL25698227 | 0.66 | CTSL (0.41) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197036-A1 | SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |