Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604991 | 0.83 | ACACB (0.41) | SLC2A1ACACB | |
| SCHEMBL24783334 | 0.81 | HTR2A (0.32) | ACACBHTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL19606410 | 0.77 | ACACB (0.31) | ACACB | |
| SCHEMBL19604932 | 0.74 | ACACB (0.38) | ACACB | |
| SCHEMBL19600911 | 0.74 | ACACB (0.33) | ACACB | |
| SCHEMBL24312112 | 0.70 | CTSL (0.46) | — | |
| SCHEMBL20324201 | 0.68 | ACACB (0.39) | ACACB | |
| SCHEMBL26748742 | 0.67 | ACACB (0.38) | ACACB | |
| SCHEMBL20325131 | 0.66 | GRM5 (0.35) | ACACBHTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL19605700 | 0.66 | ACACB (0.31) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197051-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |