SCHEMBL1960706

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10933400	1.00	SRC (0.46)	SRCESR1ESR2PDCD1CD274
	SCHEMBL18920459	0.83	CHRNA7 (0.50)	CYP2C19LMNAALDH1A1GAA
	SCHEMBL18946105	0.83	CHRNA7 (0.50)	CYP2C19LMNAALDH1A1GAA
	SCHEMBL18920460	0.83	CHRNA7 (0.50)	CYP2C19LMNAALDH1A1GAA
	SCHEMBL222001	0.83	ALDH1A1 (0.51)	SRCLMNACYP2D6ALDH1A1GAA
	SCHEMBL628680	0.83	ALDH1A1 (0.51)	SRCLMNACYP2D6ALDH1A1GAA
	SCHEMBL10540988	0.83	ALDH1A1 (0.51)	SRCLMNACYP2D6ALDH1A1GAA
	SCHEMBL5184055	0.82	AOC3 (0.42)	CYP2C19TDP1CYP1A2ALDH1A1GAA
	SCHEMBL2089224	0.82	AOC3 (0.42)	CYP2C19TDP1CYP1A2ALDH1A1GAA
	SCHEMBL756439	0.82	AOC3 (0.42)	CYP2C19TDP1CYP1A2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.