SCHEMBL628680

SCHEMBL628680

CN(C)C(C(=O)O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
GAA P10253 1/20 0.51
CYP2D6 P10635 1/20 0.50
SRC P12931 1/20 0.50
LMNA P02545 3/20 0.48
MAPK1 P28482 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ELOVL1 Q9BW60 1/20 0.45
NR4A2 P43354 1/20 0.43
ALOX5 P09917 1/20 0.42
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA4 P43681 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10540988 1.00 ALDH1A1 (0.51) ALDH1A1GAACYP2D6SRCLMNA
SCHEMBL222001 1.00 ALDH1A1 (0.51) ALDH1A1GAACYP2D6SRCLMNA
Hydrochloric Acid SCHEMBL2554908 0.98 ALDH1A1 (0.50) ALDH1A1GAACYP2D6SRCLMNA
Hydrochloric Acid SCHEMBL571538 0.98 ALDH1A1 (0.50) ALDH1A1GAACYP2D6SRCLMNA
Hydrochloric Acid SCHEMBL2552119 0.98 ALDH1A1 (0.50) ALDH1A1GAACYP2D6SRCLMNA
SCHEMBL18510081 0.86 SRC (0.50) ALDH1A1GAACYP2D6SRCLMNA
SCHEMBL3329130 0.84 ALDH1A1 (0.50) ALDH1A1GAACYP2D6SRCLMNA
SCHEMBL8921482 0.84 ALDH1A1 (0.50) ALDH1A1GAACYP2D6SRCLMNA
SCHEMBL30900470 0.84 SRC (0.48) ALDH1A1GAACYP2D6SRCLMNA
SCHEMBL8273288 0.84 ALDH1A1 (0.50) ALDH1A1GAACYP2D6SRCLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076437-A1 CHEMICALLY REVERSIBLE 2´-OH ACYLATION PROTECTS RNA FROM HYDROLYTIC AND ENZYMATIC DEGRADATION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-04-10 WO claimed
US-20240093184-A1 CHEMICALLY REVERSIBLE 2`-OH ACYLATION PROTECTS RNA FROM HYDROLYTIC AND ENZYMATIC DEGRADATION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2024-03-21 US claimed
CN-111777520-B Synthesis method of multi-substituted dimethylamino phenyl acetic acid compound 苏州爱玛特生物科技有限公司 2023-04-07 CN claimed
CN-111777520-A Synthesis method of multi-substituted dimethylamino phenyl acetic acid compound 苏州爱玛特生物科技有限公司 2020-10-16 CN claimed
US-6353041-B1 PLASTICS FOR SEALING ROOTS OF TEETH KERR CORPORATION 2002-03-05 US claimed
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2025-11-13 US disclosed
WO-2025076437-A1 CHEMICALLY REVERSIBLE 2´-OH ACYLATION PROTECTS RNA FROM HYDROLYTIC AND ENZYMATIC DEGRADATION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-04-10 WO disclosed
EP-4532484-A1 ROCK INHIBITORS AND USES THEREOF DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2025-04-09 EP disclosed
US-20250019377-A1 1, 4-OXAZEPANE DERIVATIVES AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2025-01-16 US disclosed
CN-119173509-A ROCK inhibitors and uses thereof 迪哲(江苏)医药股份有限公司 2024-12-20 CN disclosed
US-20240376128-A1 N-CYCLOPROPYLPYRIDO [4, 3-D] PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-11-14 US disclosed
EP-4387967-A1 1, 4-OXAZEPANE DERIVATIVES AND USES THEREOF Jacobio Pharmaceuticals Co., Ltd. (CN) 2024-06-26 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed
US-5463077-A Exhibit substance P antagonist activity RHONE-POULENC RORER S.A. (FR) 1995-10-31 US disclosed
US-4846877-A CYCLIC DIMERS OF PHENYLGLYCINE TEIJIN LIMITED (JP) 1989-07-11 US disclosed
US-4772314-A PHENYLGLYCINES, MONOMERIC TEIJIN LIMITED (JP) 1988-09-20 US disclosed
US-4486179-A ESTERS OF SYRINGIC ACID AS ANTICARIES AGENTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1984-12-04 US disclosed
US-4268525-A Amidoximether insecticides MOBIL OIL CORPORATION (US) 1981-05-19 US disclosed
US-4069385-A FROM AN OLEFIN AND AN ORGANIC PEROXIDE WITH COPPER-SCHIFF BASE COMPEX AS CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF ROCK1, ROCK2, RHOA ALDH1A1 2229/4885GAA 966/4885CYP2D6 3580/4885
US-20250019377-A1 1, 4-OXAZEPANE DERIVATIVES AND USES THEREOF CYP11B2, CYP21A2, CYP11B1 ALDH1A1 354/4885GAA 774/4885CYP2D6 32/4885
US-20240376128-A1 N-CYCLOPROPYLPYRIDO [4, 3-D] PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF CYP4A11, CYP4B1, DHPS ALDH1A1 311/4885GAA 1775/4885CYP2D6 8/4885
US-20240093184-A1 CHEMICALLY REVERSIBLE 2`-OH ACYLATION PROTECTS RNA FROM HYDROLYTIC AND ENZYMATIC DEGRADATION RNGTT, NSUN2, NSUN3 ALDH1A1 1562/4885GAA 742/4885CYP2D6 2587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.