Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623314 | 0.81 | MTNR1A (0.56) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| SCHEMBL4433221 | 0.78 | MTNR1A (0.49) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| SCHEMBL16866618 | 0.77 | MTNR1A (0.51) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| SCHEMBL4384511 | 0.75 | LOXL2 (0.63) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| SCHEMBL11186816 | 0.75 | PAM (0.53) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| SCHEMBL24305809 | 0.73 | MTNR1A (0.43) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| SCHEMBL11856052 | 0.73 | LOXL2 (0.56) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| SCHEMBL170083 | 0.73 | HSD17B10 (0.56) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| 2-Indolylmethanamine SCHEMBL1616223 | 0.73 | LOXL2 (1.00) | LOXL2MAPK1MTNR1AMTNR1BKDM4E | |
| 2-Indolylmethanamine SCHEMBL29738289 | 0.73 | LOXL2 (1.00) | LOXL2MAPK1MTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011066869-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2011-06-09 | — | — | WO | disclosed |