Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623314 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BKDM4EALDH1A1LOXL2 | |
| SCHEMBL16866618 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EALDH1A1LOXL2 | |
| SCHEMBL1960980 | 0.78 | LOXL2 (0.56) | MTNR1AMTNR1BKDM4EALDH1A1LOXL2 | |
| SCHEMBL7428568 | 0.77 | KDM4E (0.52) | MTNR1AMTNR1BKDM4EALDH1A1GLA | |
| SCHEMBL7421572 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1GLAMAPK1TSHR | |
| SCHEMBL2111019 | 0.74 | LOXL2 (0.58) | MTNR1AMTNR1BKDM4EALDH1A1LOXL2 | |
| SCHEMBL29045739 | 0.74 | FLT3 (0.46) | KDM4EALDH1A1MAPK1FLT3TSHR | |
| SCHEMBL3468800 | 0.73 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EALDH1A1LOXL2 | |
| SCHEMBL4280580 | 0.73 | LOXL2 (0.56) | MTNR1AMTNR1BKDM4EALDH1A1LOXL2 | |
| SCHEMBL15717620 | 0.72 | LOXL2 (0.47) | MTNR1AMTNR1BKDM4EALDH1A1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507926-A | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC | 2015-04-08 | — | — | CN | disclosed |
| EP-2121601-A2 | NOVEL INDOLE DERIVATIVES, METHODS FOR PREPARING SAME, AND USE THEREOF PARTICULARLY AS ANTIBACTERIAL AGENTS | Université Joseph Fourier (FR) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110690-A2 | NOVEL INDOLE DERIVATIVES, METHODS FOR PREPARING SAME, AND USE THEREOF PARTICULARLY AS ANTIBACTERIAL AGENTS | UNIVERSITE JOSEPH FOURIER (FR) | 2008-09-18 | — | — | WO | disclosed |