Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14813229 | 0.82 | ALDH1A1 (0.43) | PTPN1ALDH1A1TDP1GAAC5AR1 | |
| SCHEMBL10939588 | 0.79 | NPSR1 (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL11498049 | 0.79 | TSPO (0.45) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL7768063 | 0.77 | CYP19A1 (0.44) | PTPN1ALDH1A1KDM4ETDP1GAA | |
| SCHEMBL11133752 | 0.76 | CA1 (0.50) | CA1CA2CA12CA4CA7 | |
| SCHEMBL22474145 | 0.76 | MAPT (0.46) | PTPN1ALDH1A1KDM4EGAAALOX5 | |
| SCHEMBL11511623 | 0.75 | ALDH1A1 (0.47) | PTPN1ACHEALDH1A1KDM4EPOLB | |
| SCHEMBL544101 | 0.75 | C5AR1 (0.44) | PTPN1ACHEALDH1A1KMT2AMEN1 | |
| SCHEMBL28908699 | 0.74 | TDP1 (0.53) | ALDH1A1KDM4EPOLBTDP1KMT2A | |
| Nitrogen SCHEMBL4600860 | 0.73 | ESR1 (0.46) | CA1CA2CA12CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246001-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2023-03-29 | — | — | EP | disclosed |
| EP-4027964-A1 | DENTAL COMPOSITION | Dentsply Sirona Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| US-11000454-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-05-11 | — | — | US | disclosed |
| WO-2021048313-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| US-20190117523-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2017198840-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |
| EP-3246001-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11000454-B2 | Dental composition | PPIP5K2, INPP5D, DCPS | PTPN1 2231/4885ACHE 1437/4885CA1 618/4885 |
| US-20190117523-A1 | DENTAL COMPOSITION | PPIP5K2, INPP5D, DCPS | PTPN1 2231/4885ACHE 1437/4885CA1 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.