Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20414969 | 0.80 | ALPL (0.37) | ALPLABCC8KCNJ11ALOX5APCYP1A2 | |
| SCHEMBL20411757 | 0.77 | ALPL (0.38) | ALPLABCC8KCNJ11SMN1; SMN2ALOX5AP | |
| SCHEMBL23901498 | 0.71 | ALOX5AP (0.39) | ALPLTP53ALOX5APCYP1A2CYP3A4 | |
| SCHEMBL23894229 | 0.71 | ALOX5AP (0.39) | ALPLTP53ALOX5APCYP1A2CYP3A4 | |
| SCHEMBL19064350 | 0.69 | KMT2A (0.43) | HPGDMAPK1ALOX15TP53HSD17B10 | |
| SCHEMBL18279960 | 0.67 | ALOX15 (0.56) | ALPLHPGDMAPK1ALOX15TP53 | |
| SCHEMBL1477167 | 0.67 | ALOX5AP (0.49) | ALPLALOX5APCYP1A2CYP3A4CYP2C8 | |
| SCHEMBL29463696 | 0.67 | ALOX5AP (0.49) | ALPLALOX5APCYP1A2CYP3A4CYP2C8 | |
| SCHEMBL19064335 | 0.67 | MAPK1 (0.55) | ALPLHPGDMAPK1ALOX15TP53 | |
| SCHEMBL12973746 | 0.67 | NPC1 (0.47) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383105-B | Iridium complex and nitrogen-containing tridentate ligand | 季昀 | 2020-01-07 | — | — | CN | disclosed |
| US-10008680-B2 | Iridium complex and nitrogen-containing tridentate ligand | NATIONAL TSING HUA UNIVERSITY (TW) | 2018-06-26 | — | — | US | disclosed |
| US-20170338426-A1 | IRIDIUM COMPLEX AND NITROGEN-CONTAINING TRIDENTATE LIGAND | NATIONAL TSING HUA UNIVERSITY (TW) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10008680-B2 | Iridium complex and nitrogen-containing tridentate ligand | AP3M1, CMKLR2, AP2M1 | ALPL 3213/4885HPGD 4643/4885MAPK1 2021/4885 |
| US-20170338426-A1 | IRIDIUM COMPLEX AND NITROGEN-CONTAINING TRIDENTATE LIGAND | AP3M1, CMKLR2, AP2M1 | ALPL 3213/4885HPGD 4643/4885MAPK1 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.