SCHEMBL1477167

SCHEMBL1477167

CC(C)(C)c1ccnc(-c2ccc(F)cc2F)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5AP P20292 2/20 0.49
▸ KMO O15229 2/20 0.46
▸ PDK1 Q15118 1/20 0.39
▸ PDK2 Q15119 1/20 0.39
▸ ALPL P05186 2/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ SENP8 Q96LD8 1/20 0.36
▸ SENP7 Q9BQF6 1/20 0.36
▸ SENP6 Q9GZR1 1/20 0.36
▸ FAAH O00519 1/20 0.35
▸ TGFBR1 P36897 2/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2C8 P10632 1/20 0.35
▸ FEN1 P39748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29463696 1.00 ALOX5AP (0.49) ALOX5APKMOPDK1PDK2ALPL
SCHEMBL29766830 0.85 KMO (0.47) ALOX5APKMOPDK1PDK2FEN1
SCHEMBL19072695 0.85 KMO (0.47) ALOX5APKMOPDK1PDK2FEN1
SCHEMBL31400262 0.85 ALOX5AP (0.45) ALOX5APNPC1RAB9AL3MBTL1CASP3
SCHEMBL13878874 0.85 ALOX5AP (0.45) ALOX5APNPC1RAB9AL3MBTL1CASP3
SCHEMBL19072696 0.81 KMO (0.54) KMOALPLMEN1NPC1RAB9A
SCHEMBL29445848 0.81 KMO (0.54) KMOALPLMEN1NPC1RAB9A
SCHEMBL29766838 0.80 KMO (0.43) ALOX5APKMOPDK1PDK2ALPL
SCHEMBL12276192 0.78 GCGR (0.40) MEN1NPC1RAB9AKMT2ACASP3
SCHEMBL503953 0.78 CCR1 (0.55) KMOALPLMEN1KMT2AFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116685694-A Method for detecting nucleotide modifications 蓝猫知识产权有限公司 2023-09-01 — — CN disclosed
CN-116323603-A Method for labeling nucleic acids 剑桥实业有限公司 2023-06-23 — — CN disclosed
EP-2508527-B1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND USES THEREOF SAMSUNG ELECTRONICS CO LTD (KR) 2015-01-07 — — EP disclosed
EP-2084171-B1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE SHOWA DENKO KK (JP) 2013-04-10 — — EP disclosed
EP-2508527-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND USE THEREFOR Showa Denko K.K. (JP) 2012-10-10 — — EP disclosed
US-20120235132-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND USES THEREOF SAMSUNG ELECTRONICS CO., LTD (KR) 2012-09-20 — — US disclosed
US-7915414-B2 Blue-emitting organometallic complexes and their application Chi, Yun (TW) 2011-03-29 — — US disclosed
US-7915414-B2 Blue-emitting organometallic complexes and their application Chi, Yun (TW) 2011-03-29 — — US disclosed
US-20090315454-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE SHOWA DENKO K.K. (JP) 2009-12-24 — — US disclosed
US-20090315454-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE SHOWA DENKO K.K. (JP) 2009-12-24 — — US disclosed
US-20090315454-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE SHOWA DENKO K.K. (JP) 2009-12-24 — — US disclosed
EP-2084171-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE Showa Denko K.K. (JP) 2009-08-05 — — EP disclosed
US-20080125591-A1 Blue-Emitting Organometallic Complexes And Their Application Chi, Yun (TW) 2008-05-29 — — US disclosed
WO-2008056799-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE SHOWA DENKO K.K. (JP) 2008-05-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090315454-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE OBTAINED BY USING THE SAME, AND USES OF THE DEVICE ELP1, RUVBL1, LIG1 ALOX5AP 3496/4885KMO 3187/4885PDK1 1771/4885
US-20080125591-A1 Blue-Emitting Organometallic Complexes And Their Application CYBA, IK, CRY1 ALOX5AP 3930/4885KMO 1175/4885PDK1 721/4885
US-20120235132-A1 IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND USES THEREOF ELP1, AGO2, IPO5 ALOX5AP 3215/4885KMO 4623/4885PDK1 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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