Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 7/20 | 0.51 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059373 | 0.71 | CMA1 (0.53) | TGFBR1BRD9CMA1HCAR1ALDH1A1 | |
| SCHEMBL2538590 | 0.70 | TDP1 (0.51) | TGFBR1ALDH1A1MAPTDYRK1AMAOA | |
| SCHEMBL9288141 | 0.70 | TUBB4A (0.47) | CMA1HCAR1NOTUMALDH1A1PTGS1 | |
| SCHEMBL21373560 | 0.70 | CMA1 (0.47) | TGFBR1BRD9CMA1HCAR1NOTUM | |
| SCHEMBL25092810 | 0.69 | TSHR (0.37) | ALDH1A1MAPTPTGS1KDM4EHPGD | |
| SCHEMBL7313548 | 0.69 | RAD52 (0.45) | ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL19614493 | 0.69 | BRD9 (0.57) | BRD9CMA1HCAR1NOTUMALDH1A1 | |
| SCHEMBL21373483 | 0.69 | CMA1 (0.46) | TGFBR1BRD9CMA1HCAR1ALDH1A1 | |
| SCHEMBL10901975 | 0.67 | NR3C1 (0.39) | ALDH1A1MAPTPTGS2KDM4E | |
| SCHEMBL25317305 | 0.67 | TUBB4A (0.50) | HCAR1ALDH1A1MAPTPTGS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215510-B1 | SUBSTITUTED IMIDAZO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL R&D INVEST S A (PT) | 2023-06-07 | — | — | EP | disclosed |
| US-20170333435-A1 | SUBSTITUTED IMIDAZO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL - BIOTECH INVESTMENTS, INC. (PT) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170333435-A1 | SUBSTITUTED IMIDAZO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GAA, GBA1, PARK7 | TGFBR1 3422/4885BRD9 2047/4885CMA1 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.