Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 4/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19614560 | 0.88 | RBP4 (0.44) | RBP4TP53PPARGCASP3TTR | |
| SCHEMBL4277141 | 0.81 | SMN1; SMN2 (0.58) | TP53CASP3ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL21089079 | 0.77 | TP53 (0.45) | TP53ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11199708 | 0.75 | DPP4 (0.43) | RBP4PPARGTTRSSTR1SSTR4 | |
| SCHEMBL30116328 | 0.73 | PPARG (0.49) | PPARGRXRARXRBRXRGALDH1A1 | |
| SCHEMBL5272098 | 0.73 | PPARG (0.49) | PPARGRXRARXRBRXRGALDH1A1 | |
| SCHEMBL28217739 | 0.73 | NPC1 (0.62) | TP53ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18697298 | 0.72 | PPARG (0.47) | PPARGRXRARXRBRXRGALDH1A1 | |
| SCHEMBL6967623 | 0.72 | PPARG (0.47) | PPARGSSTR1SSTR4RXRARXRB | |
| SCHEMBL667777 | 0.72 | PPARG (0.51) | RBP4PPARGRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334846-A1 | SUBSTITUTED AZETIDINYL COMPOUNDS AS GLYT1 INHIBITORS | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334846-A1 | SUBSTITUTED AZETIDINYL COMPOUNDS AS GLYT1 INHIBITORS | GLRA1, AGXT, B4GALT1 | RBP4 1700/4885TP53 1897/4885PPARG 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.