SCHEMBL1961608

SCHEMBL1961608

C=CC(=O)Nc1ccccc1Nc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 6/20 0.67
FABP4 P15090 1/20 0.51
BTK Q06187 2/20 0.48
MAPT P10636 3/20 0.48
KDM4E B2RXH2 1/20 0.48
EGFR P00533 2/20 0.47
ITK Q08881 2/20 0.47
FYN P06241 1/20 0.47
SRC P12931 1/20 0.47
PTPN1 P18031 1/20 0.46
PTPN11 Q06124 1/20 0.46
GAA P10253 1/20 0.46
GFER P55789 1/20 0.46
ALOX15 P16050 1/20 0.45
F13A1 P00488 1/20 0.44
LMNA P02545 1/20 0.44
TGM1 P22735 1/20 0.44
TGM3 Q08188 1/20 0.44
MAPK3 P27361 1/20 0.44
CASP3 P42574 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11306215 0.87 TGM2 (0.65) TGM2MAPTEGFRITKSRC
SCHEMBL613090 0.87 TGM2 (0.65) TGM2BTKMAPTKDM4EEGFR
SCHEMBL31228347 0.87 TGM2 (0.65) TGM2BTKMAPTKDM4EEGFR
SCHEMBL19501015 0.84 TGM2 (0.70) TGM2MAPTKDM4EEGFRGAA
SCHEMBL2761954 0.83 TGM2 (0.62) TGM2MAPTKDM4EEGFRPTPN1
SCHEMBL23591752 0.83 TGM2 (0.68) TGM2MAPTMAPK3
SCHEMBL11306206 0.83 TGM2 (0.68) TGM2MAPTKDM4EEGFRGAA
SCHEMBL29824749 0.83 TGM2 (0.68) TGM2MAPTMAPK3
SCHEMBL261812 0.81 TGM2 (0.85) TGM2MAPTEGFRITKFYN
SCHEMBL10938927 0.81 KDM4E (0.67) MAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2222910-B1 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INT INC (US) 2015-08-26 EP disclosed
CN-103119391-A Ballistic resistant composite material with enhanced shatter resistance HONEYWELL INT INC 2013-05-22 CN disclosed
CN-101952499-B Environmentally resistant ballistic composites based on nitrile rubber binders HONEYWELL INT INC 2012-08-29 CN disclosed
US-8158540-B2 Environmentally resistant ballistic composite based on a nitrile rubber binder HONEYWELL INTERNATIONAL INC. (US) 2012-04-17 US disclosed
US-8080486-B1 Ballistic shield composites with enhanced fragment resistance HONEYWELL INTERNATIONAL INC. (US) 2011-12-20 US disclosed
US-20110143086-A1 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INTERNATIONAL INC. (US) 2011-06-16 US disclosed
CN-101952499-A Environmentally resistant ballistic composites based on nitrile rubber binders HONEYWELL INT INC 2011-01-19 CN disclosed
US-7858540-B2 Environmentally resistant ballistic composite based on a nitrile rubber binder HONEYWELL INTERNATIONAL INC. (US) 2010-12-28 US disclosed
EP-2222910-A2 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER Honeywell International Inc. (US) 2010-09-01 EP disclosed
WO-2009085674-A2 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INTERNATIONAL INC. (US) 2009-07-09 WO disclosed
US-5861212-A LATEX OF CARBOXYLATED HIGHLY SATURATED NITRILE-CONJUGATED DIENE COPOLYMER RUBBER, RESORCINOL-FORMALDEHYDE RESIN, AND AROMATIC EPOXY RESIN; BELTS NIPPON ZEON CO., LTD. (JP) 1999-01-19 US disclosed
US-5783625-A SELF-CROSSLINKING LATEX CONTAINING HYDROGENATED RUBBER COPOLYMERS OF UNSATURATED NITRILES, CARBOXYLIC ACIDS AND CONJUGATED DIENES BLENDED WITH RESORCINOL-FORMALDEHYDE RESIN, FOR BONDING TO FABRICS, ABRASION, WATER AND HEAT RESISTANCE NIPPON ZEON CO., LTD. (JP) 1998-07-21 US disclosed
EP-0704508-B1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO (JP) 1997-09-17 EP disclosed
EP-0747458-A1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO., LTD. (JP) 1996-12-11 EP disclosed
EP-0704508-A1 Adhesive composition and composite of rubber with fiber NIPPON ZEON CO., LTD. (JP) 1996-04-03 EP disclosed
EP-0285293-B1 Bound antioxidant masterbatches 3I RES EXPL LTD (GB) 1994-02-02 EP disclosed
US-4354007-A Process for preparing oxidatively-stable polymers SCOTT GERALD 1982-10-12 US disclosed
US-4300615-A Fabric composite and rubber reinforced therewith THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-11-17 US disclosed
US-4213892-A 2- AND/OR 6-TERTIARY ALKYL PHENOL SCOTT GERALD (GB) 1980-07-22 US disclosed
US-3975414-A N,N-bis(4-anilinophenyl)-4,7-dithia-5-methyldecanediamide and related compounds useful as polymer stabilizers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-08-17 US disclosed