SCHEMBL196175

SCHEMBL196175

N#CCc1ccc(-c2ccc(CC#N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.50
TNF P01375 1/20 0.46
FLT3 P36888 2/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
PIK3CA P42336 3/20 0.40
PIK3CG P48736 3/20 0.40
ENPP2 Q13822 1/20 0.39
CHEK1 O14757 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
PKM P14618 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
PIK3CD O00329 1/20 0.36
ABL1 P00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23137321 1.00 MMP3 (0.50) MMP3TNFFLT3KMT2AKDM4E
SCHEMBL30439382 0.92 MMP3 (0.50) MMP3TNFFLT3KMT2AKDM4E
SCHEMBL2154504 0.91 KMT2A (0.47) MMP3TNFFLT3KMT2AKDM4E
SCHEMBL343612 0.90 MMP3 (0.53) MMP3TNFFLT3KMT2AKDM4E
SCHEMBL4667203 0.88 MMP3 (0.67) MMP3KMT2AABL1
SCHEMBL2773349 0.88 MAOB (0.47) MMP3TNFFLT3KMT2ARXRA
SCHEMBL10899606 0.88 CYP2A6 (0.52) MMP3TNFFLT3KMT2AKDM4E
SCHEMBL9925859 0.88 NAAA (0.44) MMP3TNFFLT3KMT2AL3MBTL1
SCHEMBL23578319 0.88 MAOB (0.47) MMP3TNFFLT3KMT2AL3MBTL1
SCHEMBL24067260 0.86 TNF (0.54) MMP3TNFFLT3KMT2APIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019650-A Sp (sp)2C covalent organic framework photo-catalytic material and preparation method and application thereof 南京师范大学 2024-11-26 CN claimed
EP-4569559-A1 GLASSY ORGANIC FRAMEWORK ION-CONDUCTIVE MEMBRANES Wisconsin Alumni Research Foundation (US) 2025-06-18 EP disclosed
CN-119019650-A Sp (sp)2C covalent organic framework photo-catalytic material and preparation method and application thereof 南京师范大学 2024-11-26 CN disclosed
CN-119019650-A Sp (sp)2C covalent organic framework photo-catalytic material and preparation method and application thereof 南京师范大学 2024-11-26 CN disclosed
US-20240055638-A1 GLASSY ORGANIC FRAMEWORK ION-CONDUCTIVE MEMBRANES WISCONSIN ALUMNI RESEARCH FOUNDATION 2024-02-15 US disclosed
WO-2024036130-A1 GLASSY ORGANIC FRAMEWORK ION-CONDUCTIVE MEMBRANES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-02-15 WO disclosed
US-11858814-B2 Reticulation of macromolecules into crystalline networks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-02 US disclosed
CN-117186412-A Silsesquioxane fluorescent porous hybrid polymer with D-A structure, preparation method thereof and application thereof in gold recovery 山东大学 2023-12-08 CN disclosed
CN-113813939-B Application of COF material based on C ═ C bond connection in preparation of chiral chromatography stationary phase 上海交通大学 2022-08-12 CN disclosed
CN-113813939-A Application of COF material based on C = C bond connection in preparation of chiral chromatography stationary phase 上海交通大学 2021-12-21 CN disclosed
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED 2011-02-24 US disclosed
US-20100292481-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2010-11-18 US disclosed
EP-2233459-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-09-29 EP disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
US-7514158-B2 Coumarin compound KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2009-04-07 US disclosed
US-7419727-B2 Organic electroluminescent device KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2008-09-02 US disclosed
US-20060192473-A1 Organic electroluminescent device KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2006-08-31 US disclosed
US-20050275341-A1 Coumarin compound KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2005-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046336-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP1M1 MMP3 4526/4885TNF 3648/4885FLT3 1832/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 MMP3 4630/4885TNF 3199/4885FLT3 2066/4885
US-20050275341-A1 Coumarin compound XPO1, VKORC1, XPO5 MMP3 1440/4885TNF 3365/4885FLT3 2658/4885
US-20100292481-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND TYR, PAH, AHR MMP3 4042/4885TNF 3076/4885FLT3 2150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.