SCHEMBL343612

SCHEMBL343612

N#CCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.53
FLT3 P36888 1/20 0.53
TAAR1 Q96RJ0 2/20 0.50
PIK3CA P42336 1/20 0.49
PIK3CG P48736 1/20 0.49
KMT2A Q03164 1/20 0.46
ABCB1 P08183 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.45
IDO1 P14902 2/20 0.45
AGXT P21549 2/20 0.45
LMNA P02545 2/20 0.45
ABCC4 O15439 1/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.45
PTGS1 P23219 1/20 0.45
HTT P42858 1/20 0.45
CNR2 P34972 1/20 0.45
TNF P01375 1/20 0.45
ALDH1A1 P00352 1/20 0.43
NAAA Q02083 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196175 0.90 MMP3 (0.50) MMP3FLT3PIK3CAPIK3CGKMT2A
SCHEMBL23137321 0.90 MMP3 (0.50) MMP3FLT3PIK3CAPIK3CGKMT2A
Benzene SCHEMBL28804146 0.85 ENPP2 (0.48) MMP3KMT2AIDO1LMNATSHR
SCHEMBL37831 0.85
Water SCHEMBL27932616 0.85 ENPP2 (0.48) MMP3KMT2AIDO1LMNATSHR
SCHEMBL1921814 0.85
Benzene SCHEMBL7517467 0.85 ENPP2 (0.48) MMP3KMT2AIDO1LMNATSHR
SCHEMBL1332411 0.85
SCHEMBL31402005 0.85
SCHEMBL27871594 0.85 ENPP2 (0.48) MMP3KMT2AIDO1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462420-A Synthesis and application research of cyano stilbene derivative 淮南师范学院 2025-02-18 CN claimed
CN-118479983-A Synthesis method of cyano stilbene derivative organic compound 淮南师范学院 2024-08-13 CN claimed
CN-118359798-A Aryl and cyano difunctional poly ɛ -caprolactone polymer and preparation method thereof 大连理工大学 2024-07-19 CN claimed
CN-117264155-A Three-component luminous covalent organic framework material based on white light emission and preparation method and application thereof 江西师范大学 2023-12-22 CN claimed
CN-117164790-A Preparation of ultrafast visual volatile amine response sensor based on covalent organic framework material 江南大学 2023-12-05 CN claimed
CN-116239759-A Conjugated two-dimensional polymer film and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-06-09 CN claimed
CN-114436891-B Color-adjustable aggregation-induced emission material and preparation method and application thereof 北京科技大学 2023-01-03 CN claimed
CN-115215813-A Method for controlling valsartan impurity 江苏新瑞药业有限公司 2022-10-21 CN claimed
CN-114702278-B Preparation process of firework and firecracker work place table top and ground anti-static building layer 醴陵市恒峰化工科技有限公司 2022-09-20 CN claimed
CN-114702278-A Preparation process of firework and firecracker work place table top and ground anti-static building layer 醴陵市恒峰化工科技有限公司 2022-07-05 CN claimed
CN-114436891-A Color-adjustable aggregation-induced emission material and preparation method and application thereof 北京科技大学 2022-05-06 CN claimed
CN-106431911-B Preparation and purification method of 4-felbinac 黄石市利福达医药化工有限公司 2021-05-28 CN claimed
CN-106431911-A Preparation and purification methods of 4-biphenylacetic acid 黄石市利福达医药化工有限公司 2017-02-22 CN claimed
CN-103751943-A Fire extinguishing composition containing nitrogenous organic compound XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-04-30 CN claimed
CN-102010317-B Method for synthesizing felbinac and derivatives thereof USTC UNIV SCIENCE TECH CN 2013-10-16 CN claimed
CN-102827167-A Octahydro-pyrrolo [3,4-b ] pyrrole derivatives and their use as histamine-3 receptor ligands ABBOTT LAB 2012-12-19 CN claimed
CN-102010317-A Method for synthesizing felbinac and derivatives thereof USTC UNIV SCIENCE TECH CN 2011-04-13 CN claimed
CN-101415709-A Octahydro-pyrrolo [3, 4-b ] pyrrole derivatives and their use as histamine-3 receptor ligands ABBOTT LAB (US) 2009-04-22 CN claimed
CN-118459418-B Hydroxamic acid HDAC inhibitor and application thereof in preparation of antitumor drugs 河北中医药大学 2025-04-08 CN disclosed
US-3931207-A ANTIARTHRITIC SMITHKLINE CORPORATION (US) 1976-01-06 US disclosed