SCHEMBL19618141

SCHEMBL19618141

Cc1ccc(N(C)c2ccc(C(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
DHFR P00374 1/20 0.42
CNR2 P34972 2/20 0.40
CNR1 P21554 1/20 0.40
CES1 P23141 1/20 0.40
ACHE P22303 2/20 0.39
BCHE P06276 1/20 0.39
ALOX5 P09917 1/20 0.37
TYR P14679 1/20 0.37
MAPT P10636 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.36
S1PR1 P21453 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4C Q9H3R0 1/20 0.35
PYCR1 P32322 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5431004 0.91 DHFR (0.46) ALDH1A1TSHRDHFRTYRTDP1
P-Cymene SCHEMBL29006180 0.85 ACHE (0.50) CHRNA7CNR2ACHEBCHEALOX5
P-Cymene SCHEMBL4860410 0.85 ACHE (0.50) CHRNA7CNR2ACHEBCHEALOX5
SCHEMBL9925446 0.85 DHFR (0.42) CHRNA7ALDH1A1TSHRDHFRCNR2
P-Cymene SCHEMBL3684076 0.85 ACHE (0.50) CHRNA7CNR2ACHEBCHEALOX5
SCHEMBL20386671 0.84 CHRNA7 (0.44) CHRNA7ALDH1A1TSHRCNR2CNR1
SCHEMBL12367721 0.84 CHRNA7 (0.44) CHRNA7ALDH1A1TSHRCNR2CNR1
P-Cymene SCHEMBL6274941 0.83 ACHE (0.47) CHRNA7CNR2ACHEBCHEALOX5
P-Cymene SCHEMBL2570692 0.83 ACHE (0.47) CHRNA7CNR2ACHEBCHEALOX5
P-Cymene SCHEMBL30626114 0.83 ACHE (0.47) CHRNA7CNR2ACHEBCHEALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) MERCK PATENT GMBH (DE) 2023-02-21 US disclosed
US-11177446-B2 Silicon containing organic fluorescent materials Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-11-16 US disclosed
EP-3544984-B1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2019-10-17 US disclosed
US-20190081253-A1 SILICON CONTAINING ORGANIC FLUORESCENT MATERIALS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed
WO-2018095888-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 WO disclosed
US-9825237-B2 Organic electroluminescent element, compound for organic electroluminescent element, and light-emitting device, display device, and illumination device using said element UDC IRELAND LIMITED (IE) 2017-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11177446-B2 Silicon containing organic fluorescent materials ORAI2, TRPA1, IK CHRNA7 1567/4885ALDH1A1 381/4885TSHR 4735/4885
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) OCIAD1, OCIAD2, AOC1 CHRNA7 2437/4885ALDH1A1 99/4885TSHR 4385/4885
US-20190081253-A1 SILICON CONTAINING ORGANIC FLUORESCENT MATERIALS ORAI2, TRPA1, IK CHRNA7 1567/4885ALDH1A1 381/4885TSHR 4735/4885
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) OCIAD1, OCIAD2, AOC1 CHRNA7 2437/4885ALDH1A1 99/4885TSHR 4385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.