Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955807 | 0.88 | CCR1 (0.48) | GRM5CCR1CCR8NOS3NOS2 | |
| SCHEMBL955898 | 0.88 | PGK1 (0.38) | GABRA1GABRG2GABRB3GABRA3PGK1 | |
| SCHEMBL1959772 | 0.81 | GRM5 (0.43) | GRM5CCR1CCR8NOS3NOS2 | |
| SCHEMBL1960817 | 0.79 | GRM5 (0.38) | GRM5CCR1CCR8NOS3NOS2 | |
| SCHEMBL29692491 | 0.77 | — | — | |
| SCHEMBL103431 | 0.77 | — | — | |
| SCHEMBL1437359 | 0.76 | IDH1 (0.37) | GRM5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL5646151 | 0.76 | GABRA1 (0.36) | GRM5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL30041313 | 0.76 | GABRA1 (0.36) | GRM5GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31078226 | 0.76 | IDH1 (0.37) | GRM5GABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9634268-B2 | Electronic device comprising metal complexes | MERCK PATENT GMBH (DE) | 2017-04-25 | — | — | US | disclosed |
| US-20120286254-A1 | ELECTRONIC DEVICE COMPRISING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-11-15 | — | — | US | disclosed |
| WO-2011066898-A1 | ELECTRONIC DEVICE CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120286254-A1 | ELECTRONIC DEVICE COMPRISING METAL COMPLEXES | AP1M1, EXOC1, EMC1 | GRM5 1556/4885CCR1 1099/4885CCR8 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.