Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KDM5C | P41229 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18561913 | 0.85 | L3MBTL1 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL31231324 | 0.84 | HDAC3 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15451914 | 0.84 | L3MBTL1 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29131546 | 0.81 | MAPT (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27908768 | 0.81 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27129877 | 0.81 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL461444 | 0.81 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15447135 | 0.80 | DPP4 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17443233 | 0.80 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27130016 | 0.80 | L3MBTL1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602620-B | Novel iridium-based complexes for ECL | 霍夫曼-拉罗奇有限公司 | 2020-08-28 | — | — | CN | disclosed |
| EP-2882764-B1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | ROCHE DIAGNOSTICS GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-9399654-B2 | Iridium-based complexes for ECL | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2016-07-26 | — | — | US | disclosed |
| EP-2882764-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | Roche Diagnostics GmbH (DE) | 2015-06-17 | — | — | EP | disclosed |
| US-20150147750-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2015-05-28 | — | — | US | disclosed |
| WO-2014019708-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | ROCHE DIAGNOSTICS GMBH (DE) | 2014-02-06 | — | — | WO | disclosed |
| US-20130004986-A1 | Use of luminescent Ir(III) and Ru(II) complexes | WESTFAELISCHE WILHELMS-UNIVERITAET MUENSTER (DE) | 2013-01-03 | — | — | US | disclosed |
| EP-2507339-A1 | USE OF LUMINESCENT IR(III) AND RU(II) COMPLEXES | Westfälische Wilhelms-Universität Münster (DE) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067401-A1 | USE OF LUMINESCENT IR(III) AND RU(II) COMPLEXES | Westfälische Wilhelms-Universität Münster (DE) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150147750-A1 | NEW IRIDIUM-BASED COMPLEXES FOR ECL | ALPL, ALDH1A3, SOD3 | HDAC3 3283/4885HDAC4 4589/4885HDAC1 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.