Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24971860 | 0.78 | LMNA (0.40) | POLBMAPTRECQLMEN1HTT | |
| SCHEMBL20751614 | 0.77 | MAOA (0.39) | KDM4EALDH1A1HPGDMEN1HTT | |
| SCHEMBL24729127 | 0.77 | KDM4E (0.42) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL24973479 | 0.76 | SIRT2 (0.39) | ALDH1A1MAPTRECQLMEN1KMT2A | |
| SCHEMBL12164861 | 0.76 | CES2 (0.39) | POLBALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL18830805 | 0.76 | ALDH1A1 (0.38) | KDM4EPOLBALDH1A1MAPTHPGD | |
| SCHEMBL25695261 | 0.75 | KDM4E (0.41) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL26324254 | 0.75 | MAPT (0.41) | KDM4EALDH1A1MAPTHPGDRECQL | |
| SCHEMBL24972568 | 0.74 | FABP3 (0.42) | HTTNPSR1TDP1L3MBTL1FABP3 | |
| SCHEMBL20613716 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2769982-B1 | Deuterated heteroleptic iridium complexes as phosphorescent material in OLEDS | UNIVERSAL DISPLAY CORP (US) | 2017-11-22 | — | — | EP | disclosed |