Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672724 | 0.80 | GPR35 (0.58) | GPR35ERN1ALDH1A1TDP1GAA | |
| SCHEMBL2129027 | 0.80 | GPR35 (0.58) | GPR35ERN1ALDH1A1TDP1GAA | |
| SCHEMBL9005479 | 0.80 | GPR35 (0.58) | GPR35PTPN1ALDH1A1TDP1S100A4 | |
| SCHEMBL17693438 | 0.80 | TSHR (0.45) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL1982757 | 0.79 | TLR8 (0.45) | GPR35ALDH1A1TDP1TSHRHPGD | |
| SCHEMBL28225964 | 0.79 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRLMNATP53 | |
| SCHEMBL27552013 | 0.79 | GPR35 (0.56) | GPR35ALDH1A1TDP1GAAGFER | |
| SCHEMBL27551991 | 0.79 | GPR35 (0.56) | GPR35ALDH1A1TDP1GAAGFER | |
| SCHEMBL21603111 | 0.79 | GPR35 (0.56) | GPR35ALDH1A1TDP1GAAGFER | |
| SCHEMBL70533 | 0.77 | GPR35 (0.75) | GPR35ERN1ALDH1A1TDP1S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327533-A1 | METHOD FOR SPECIFIC CLEAVAGE OF C Alpha-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE | SHIMADZU CORPORATION (JP) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327533-A1 | METHOD FOR SPECIFIC CLEAVAGE OF C Alpha-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE | CPN1, CYBA, CRYAB | GPR35 2276/4885PTPN1 3643/4885ERN1 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.