Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPD | P32754 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104452 | 0.81 | PKM (0.59) | TSHRPKMKDM4EHPGDHSD17B10 | |
| SCHEMBL29740471 | 0.81 | PKM (0.59) | TSHRPKMKDM4EHPGDHSD17B10 | |
| SCHEMBL19622615 | 0.80 | GPR35 (0.53) | TSHRKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL1497989 | 0.78 | TSHR (0.60) | TSHRPKMKDM4EHPGDHSD17B10 | |
| SCHEMBL9718761 | 0.77 | HPSE (0.56) | TSHRKDM4EMAPTHTTALDH1A1 | |
| SCHEMBL4750504 | 0.77 | HPSE (0.56) | TSHRKDM4EMAPTHTTALDH1A1 | |
| SCHEMBL933092 | 0.77 | KDM4E (0.58) | TSHRKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL1982757 | 0.77 | TLR8 (0.45) | TSHRHPDHPGDMAPK1ALDH1A1 | |
| SCHEMBL28225964 | 0.77 | ALDH1A1 (0.60) | TSHRHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL30490414 | 0.77 | TSHR (0.58) | TSHRPKMKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810047-A | (R) synthetic method of the chiral intermediate of -3- Phenylpiperidine or/and (S) -3- Phenylpiperidine and Ni Lapani | 上海博邦医药科技有限公司 | 2019-05-28 | — | — | CN | disclosed |
| US-9738753-B2 | Programmed degradation of polymers derived from biomass | NDSU RESEARCH FOUNDATION (US) | 2017-08-22 | — | — | US | disclosed |
| US-20160108172-A1 | PROGRAMMED DEGRADATION OF POLYMERS DERIVED FROM BIOMASS | NORTH DAKOTA STATE UNIVERSITY | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108172-A1 | PROGRAMMED DEGRADATION OF POLYMERS DERIVED FROM BIOMASS | PARG, PPOX, PGLS | TSHR 4715/4885PKM 323/4885HPD 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.