SCHEMBL196246

SCHEMBL196246

CC(=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2125881 0.91 THRB (0.55) THRBLMNA
SCHEMBL16172576 0.88 THRB (0.59) THRBLMNA
SCHEMBL2124778 0.88 THRB (0.59) THRBLMNA
SCHEMBL2124333 0.88 THRB (0.59) THRBLMNA
SCHEMBL28019633 0.88 THRB (0.59) THRBLMNA
SCHEMBL16172577 0.88 THRB (0.59) THRBLMNA
SCHEMBL14281288 0.87 THRB (0.35) THRBLMNA
SCHEMBL430486 0.80 THRB (0.35) THRBLMNA
SCHEMBL10053403 0.79 LMNA (0.39) THRBLMNA
SCHEMBL13227921 0.79 THRB (0.31) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025091685-A1 FLUORINATED LIQUID COMPOSITION AND USE THEREOF 深圳市鸿富诚新材料股份有限公司 2025-05-08 WO claimed
CN-119552067-A Perfluoro ketone compound and preparation method and application thereof 深圳市亿万克数据设备科技有限公司 2025-03-04 CN claimed
CN-117603661-A Fluorinated liquid composition and application thereof 武汉肯达科讯科技有限公司 2024-02-27 CN claimed
US-8418530-B1 Compositions and methods for detecting leaks in HVAC/R systems MAINSTREAM ENGINEERING CORPORATION (US) 2013-04-16 US claimed
US-7960331-B2 Replacement solvents having improved properties and methods of using the same GRZYLL LAWRENCE R 2011-06-14 US claimed
WO-2009019219-A2 METHODS OF USING A SOLVENT OR A FOAM BLOWING AGENT Solvay (Société Anonyme) (BE) 2009-02-12 WO claimed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US claimed
US-7138549-B2 Electrooptic compounds and methods for making BATTELLE MEMORIAL INSTITUTE (US) 2006-11-21 US claimed
US-20050188697-A1 Fluorinated ketone and fluorinated ethers as working fluids for thermal energy conversion HONEYWELL CORPORATION 2005-09-01 US claimed
US-20050159623-A1 Electrooptic compounds and methods for making MCGINNISS VINCENT D (US) 2005-07-21 US claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-4393183-A STORAGE STABILITY, BONDING STRENGTH TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1983-07-12 US claimed
US-12516275-B2 Composition; cleaning agent, aerosol composition, draining agent, foaming agent, or heat-transfer medium containing the composition; system using the heat-transfer medium; and method of cleaning articles CENTRAL GLASS COMPANY, LIMITED (JP) 2026-01-06 US disclosed
US-20250343048-A1 ETCHING METHOD RESONAC CORPORATION (JP) 2025-11-06 US disclosed
US-4601917-A CHEMICAL VAPOR DEPOSITION M&T CHEMICALS INC. (US) 1986-07-22 US disclosed
EP-0154528-A2 Alkene, alkyne or cycloalkylene derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-11 EP disclosed
US-4393183-A STORAGE STABILITY, BONDING STRENGTH TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1983-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159623-A1 Electrooptic compounds and methods for making EPCAM, ELOB, EED THRB 1451/4885LMNA 882/4885MAPT 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.