SCHEMBL430486

SCHEMBL430486

CC(=O)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.33
LIPA P38571 1/20 0.31
TSHR P16473 1/20 0.31
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10053403 0.85 LMNA (0.39) THRBLMNATSHRTHPOFFAR3
SCHEMBL196246 0.80 THRB (0.43) THRBLMNA
SCHEMBL14281288 0.79 THRB (0.35) THRBLMNATSHRTHPOFFAR3
SCHEMBL15461769 0.78 ALDH1A1 (0.33) THRB
SCHEMBL2125881 0.78 THRB (0.55) THRBLMNA
SCHEMBL810975 0.76 LMNA (0.31) LMNATSHR
SCHEMBL28019633 0.76 THRB (0.59) THRBLMNA
SCHEMBL2124333 0.76 THRB (0.59) THRBLMNA
SCHEMBL16172576 0.76 THRB (0.59) THRBLMNA
SCHEMBL2124778 0.76 THRB (0.59) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161911-A1 POLYMERS FOR THE REMOVAL OF PFAS FROM AQUEOUS COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME GULF COAST ENVIRONMENTAL SYSTEMS LLC (DBA CONIFER SYSTEMS) 2025-05-22 US claimed
WO-2025106778-A1 POLYMERS FOR THE REMOVAL OF PFAS FROM AQUEOUS COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME LUTUM TECHNOLOGY, LLC (US) 2025-05-22 WO claimed
WO-2025091685-A1 FLUORINATED LIQUID COMPOSITION AND USE THEREOF 深圳市鸿富诚新材料股份有限公司 2025-05-08 WO claimed
CN-119552067-A Perfluoro ketone compound and preparation method and application thereof 深圳市亿万克数据设备科技有限公司 2025-03-04 CN claimed
CN-117603661-A Fluorinated liquid composition and application thereof 武汉肯达科讯科技有限公司 2024-02-27 CN claimed
WO-2009019219-A2 METHODS OF USING A SOLVENT OR A FOAM BLOWING AGENT Solvay (Société Anonyme) (BE) 2009-02-12 WO claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-20250343048-A1 ETCHING METHOD RESONAC CORPORATION (JP) 2025-11-06 US disclosed
US-20250161911-A1 POLYMERS FOR THE REMOVAL OF PFAS FROM AQUEOUS COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME GULF COAST ENVIRONMENTAL SYSTEMS LLC (DBA CONIFER SYSTEMS) 2025-05-22 US disclosed
WO-2025106778-A1 POLYMERS FOR THE REMOVAL OF PFAS FROM AQUEOUS COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME LUTUM TECHNOLOGY, LLC (US) 2025-05-22 WO disclosed
WO-2025091685-A1 FLUORINATED LIQUID COMPOSITION AND USE THEREOF 深圳市鸿富诚新材料股份有限公司 2025-05-08 WO disclosed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
EP-0154528-A2 Alkene, alkyne or cycloalkylene derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-11 EP disclosed
EP-0104734-A1 Triazole antifungal agents Pfizer Limited (GB) 1984-04-04 EP disclosed
US-4031103-A BRONCHODILATOR AGENTS, 2,6-DIAMINOPYRIDINE, DIKETONE COMPOUND MERCK SHARP & DOHME (I.A.) CORPORATION (US) 1977-06-21 US disclosed
US-3993656-A BRONCHODILATOR, HYPOTENSIVES MERCK & CO., INC. (US) 1976-11-23 US disclosed
US-3962262-A HYPOTENSIVE AGENTS, BRONCHODILATORS MERCK & CO., INC. (US) 1976-06-08 US disclosed