SCHEMBL2124333

SCHEMBL2124333

CC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
GAA P10253 1/20 0.35
LMNA P02545 1/20 0.35
CA2 P00918 10/20 0.34
CA1 P00915 9/20 0.34
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
F2 P00734 2/20 0.31
PRSS1 P07477 2/20 0.31
PRSS2 P07478 2/20 0.31
PRSS3 P35030 2/20 0.31
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2124778 1.00 THRB (0.59) THRBGAALMNACA2CA1
SCHEMBL16172577 1.00 THRB (0.59) THRBGAALMNACA2CA1
SCHEMBL28019633 1.00 THRB (0.59) THRBGAALMNACA2CA1
SCHEMBL16172576 1.00 THRB (0.59) THRBGAALMNACA2CA1
SCHEMBL2125881 0.97 THRB (0.55) THRBGAALMNACA2CA1
SCHEMBL196246 0.88 THRB (0.43) THRBLMNA
SCHEMBL14281288 0.82 THRB (0.35) THRBLMNA
SCHEMBL18017005 0.81 THRB (0.64) THRBHDAC1HDAC7HDAC8HDAC6
SCHEMBL18017015 0.81 THRB (0.39) THRBHDAC1HDAC7HDAC8HDAC6
SCHEMBL18017024 0.81 THRB (0.39) THRBHDAC1HDAC7HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552067-A Perfluoro ketone compound and preparation method and application thereof 深圳市亿万克数据设备科技有限公司 2025-03-04 CN claimed
CN-109321133-B Coating composition and preparation method thereof, coated piece and preparation method thereof, and household appliance 广东美的厨房电器制造有限公司 2022-02-11 CN claimed
CN-108795290-B Coating composition and coating material and coating layer and silicon oxide coating layer and article having the coating layer and method for forming coating layer on substrate surface 广东美的厨房电器制造有限公司 2021-03-02 CN claimed
CN-109370426-B Coating composition and preparation method thereof, coated piece and preparation method thereof, and household appliance 广东美的厨房电器制造有限公司 2020-12-22 CN claimed
US-12576297-B2 Apparatus and methods for sonochemical degradation of per- and polyfluoroalkyl substances THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-17 US disclosed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
CN-119552067-A Perfluoro ketone compound and preparation method and application thereof 深圳市亿万克数据设备科技有限公司 2025-03-04 CN disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
CN-109321133-B Coating composition and preparation method thereof, coated piece and preparation method thereof, and household appliance 广东美的厨房电器制造有限公司 2022-02-11 CN disclosed
CN-109096915-B Coating composition and coating material and coating layer and silicon oxide coating layer and article having the coating layer and method for forming coating layer on substrate surface 广东美的厨房电器制造有限公司 2021-04-20 CN disclosed
CN-108795290-B Coating composition and coating material and coating layer and silicon oxide coating layer and article having the coating layer and method for forming coating layer on substrate surface 广东美的厨房电器制造有限公司 2021-03-02 CN disclosed
CN-109370426-B Coating composition and preparation method thereof, coated piece and preparation method thereof, and household appliance 广东美的厨房电器制造有限公司 2020-12-22 CN disclosed
US-8716531-B2 Method for producing norbornene derivative JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-05-06 US disclosed
US-20120108851-A1 METHOD FOR PRODUCING NORBORNENE DERIVATIVE JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-05-03 US disclosed
EP-2444386-A1 PROCESS FOR PREPARATION OF NORBORNENE DERIVATIVES JX Nippon Oil & Energy Corporation (JP) 2012-04-25 EP disclosed
JP-2001279296-A AZEOTROPE OR AZEOTROPE-LIKE COMPOSITION COMPRISING FLUORINE-CONTAINING KETONE AND ALCOHOL NATL INST OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY METI 2001-10-10 JP disclosed
US-4000150-A HEAT EXCHANGE MEDIA, SURFACTANTS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-12-28 US disclosed
US-3965092-A HEAT EXCHANGE, SURFACTANTS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576297-B2 Apparatus and methods for sonochemical degradation of per- and polyfluoroalkyl substances PFAS, PIEZO1, UFL1 THRB 1680/4885GAA 3996/4885LMNA 1329/4885
US-20120108851-A1 METHOD FOR PRODUCING NORBORNENE DERIVATIVE UGT1A8, UGT8, ALG8 THRB 3511/4885GAA 1187/4885LMNA 1376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.