Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PPM1D | O15297 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17680609 | 0.76 | USP7 (0.41) | CREBBPBRD4ALDH1A1 | |
| SCHEMBL543484 | 0.74 | ATM (0.40) | ATMNPSR1LMNATSHRHTT | |
| SCHEMBL21494779 | 0.72 | HTR2A (0.42) | NPSR1ALDH1A1 | |
| SCHEMBL17748782 | 0.70 | CEL (0.42) | ATMPPM1DEEDALDH1A1RAB9A | |
| SCHEMBL28786058 | 0.70 | TDP1 (0.47) | ADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL28264564 | 0.70 | HTR2A (0.41) | — | |
| SCHEMBL30006395 | 0.69 | ICMT (0.39) | CREBBPBRD4ADORA2AADORA1SYK | |
| SCHEMBL14235857 | 0.69 | PDE4D (0.41) | ATMLMNAHRH1HRH3ALDH1A1 | |
| SCHEMBL24852679 | 0.68 | HDAC6 (0.45) | NPSR1HTTALDH1A1RAB9A | |
| SCHEMBL3247871 | 0.67 | ATM (0.58) | ATMNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |