Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533659 | 0.90 | HPGDS (0.48) | HPGDSALDH1A1MAPTRAB9ALTA4H | |
| SCHEMBL19544753 | 0.88 | HPGDS (0.46) | HPGDSALDH1A1MAPTRAB9ALTA4H | |
| SCHEMBL19624943 | 0.84 | ALDH1A1 (0.53) | HPGDSALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL27321802 | 0.82 | RAB9A (0.63) | HPGDSALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL2838238 | 0.81 | ALDH1A1 (0.54) | HPGDSALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL19533660 | 0.80 | HPGDS (0.78) | HPGDSALDH1A1MAPTRAB9AL3MBTL1 | |
| SCHEMBL6343968 | 0.76 | ALDH1A1 (0.47) | HPGDSALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL19544658 | 0.76 | SCN9A (0.54) | HPGDSALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL2255952 | 0.76 | PDE4B (0.56) | MAPTRAB9ACYP1A2CYP2C19POLB | |
| SCHEMBL19544677 | 0.75 | PTGS2 (0.48) | HPGDSALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |