Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090743 | 0.84 | ACACB (0.52) | ACACBACACAMEN1USP2LMNA | |
| SCHEMBL19627290 | 0.84 | MAPT (0.45) | ACACBACACAMEN1LMNAMAPT | |
| SCHEMBL19627285 | 0.78 | MAPT (0.52) | ACACBACACAMAPTKMT2AALDH1A1 | |
| SCHEMBL9297209 | 0.77 | ALDH1A1 (0.46) | ACACBMEN1USP2LMNAGAA | |
| SCHEMBL17445755 | 0.77 | ICAM1 (0.36) | CARM1PRMT6FFAR1 | |
| SCHEMBL19627293 | 0.75 | LMNA (0.40) | ACACBACACAMEN1LMNAMAPT | |
| SCHEMBL8415231 | 0.75 | CYP19A1 (0.45) | ACACBMAPTALDH1A1RAB9ACARM1 | |
| SCHEMBL18416884 | 0.75 | ALDH1A1 (0.49) | MEN1USP2LMNAKMT2AMAPK1 | |
| SCHEMBL12090874 | 0.73 | ACACB (0.44) | ACACBACACAMEN1GAAMAPT | |
| SCHEMBL9502793 | 0.72 | ACACB (0.44) | ACACBALDH1A1RAB9ACARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335192-A1 | Polymerisable Liquid Crystal Material and Polymerised Liquid Crystal Film | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | US | disclosed |