Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 6/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627300 | 0.91 | KMT2A (0.34) | LMNAACACBACACAMAPTKMT2A | |
| SCHEMBL19627290 | 0.89 | MAPT (0.45) | LMNAACACBACACAMAPTKMT2A | |
| SCHEMBL19627286 | 0.75 | ACACB (0.41) | LMNAACACBACACAMAPTKMT2A | |
| SCHEMBL17445755 | 0.71 | ICAM1 (0.36) | FFAR1 | |
| SCHEMBL9507872 | 0.70 | NQO1 (0.54) | LMNAMAPTKMT2AMEN1KDM4E | |
| SCHEMBL6451238 | 0.68 | ALDH1A1 (0.55) | LMNAMAPTKMT2AMMP2MMP9 | |
| SCHEMBL8983166 | 0.68 | SMN1; SMN2 (0.51) | LMNAMAPTKMT2AMMP2MMP9 | |
| SCHEMBL19460696 | 0.67 | KMT2A (0.67) | LMNAMAPTKMT2AALDH1A1PARP10 | |
| SCHEMBL3419802 | 0.67 | NQO1 (0.64) | LMNAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL18570814 | 0.65 | CACNA1C (0.54) | LMNAMAPTATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335192-A1 | Polymerisable Liquid Crystal Material and Polymerised Liquid Crystal Film | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | US | disclosed |