Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627293 | 0.89 | LMNA (0.40) | MAPTL3MBTL1LMNAATMACACB | |
| SCHEMBL19627286 | 0.84 | ACACB (0.41) | MAPTL3MBTL1LMNAACACBACACA | |
| SCHEMBL19627300 | 0.80 | KMT2A (0.34) | MAPTL3MBTL1LMNAACACBACACA | |
| SCHEMBL17445755 | 0.80 | ICAM1 (0.36) | FFAR1 | |
| SCHEMBL9507872 | 0.78 | NQO1 (0.54) | MAPTL3MBTL1LMNAATMLTA4H | |
| SCHEMBL18570814 | 0.73 | CACNA1C (0.54) | MAPTL3MBTL1LMNAATMLTA4H | |
| SCHEMBL17897403 | 0.73 | CHRNB2 (0.35) | — | |
| SCHEMBL9771543 | 0.70 | KMT2A (0.43) | MAPTL3MBTL1NQO1TDP1MEN1 | |
| SCHEMBL28882240 | 0.70 | ALDH1A1 (0.42) | MAPTTDP1MEN1KMT2ATSHR | |
| SCHEMBL8633956 | 0.69 | MAPT (0.41) | MAPTL3MBTL1LMNAATMLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170335192-A1 | Polymerisable Liquid Crystal Material and Polymerised Liquid Crystal Film | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | US | disclosed |