SCHEMBL19628282

SCHEMBL19628282

COc1cc(C(O)C(CO)Oc2ccccc2OC)ccc1OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.51
PPARD Q03181 1/20 0.51
PPARA Q07869 1/20 0.51
MMP9 P14780 1/20 0.51
F2 P00734 2/20 0.47
F10 P00742 2/20 0.47
PRSS1 P07477 2/20 0.47
F7 P08709 2/20 0.47
PRSS2 P07478 1/20 0.47
F3 P13726 1/20 0.47
PRSS3 P35030 1/20 0.47
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965419 0.91 MMP9 (0.44) PPARGPPARDPPARAMMP9F2
SCHEMBL9579548 0.89 PPARG (0.63) PPARGPPARDPPARAMMP9SMN1; SMN2
SCHEMBL22833918 0.89 PPARG (0.63) PPARGPPARDPPARAMMP9SMN1; SMN2
SCHEMBL29940872 0.89 PPARG (0.63) PPARGPPARDPPARAMMP9SMN1; SMN2
SCHEMBL19632845 0.87 MGAM (0.42) PPARGPPARDPPARAMMP9KMT2A
SCHEMBL1078636 0.87 PPARG (0.55) PPARGPPARDPPARAMMP9SMN1; SMN2
SCHEMBL17997504 0.87 PPARG (0.55) PPARGPPARDPPARAMMP9SMN1; SMN2
SCHEMBL17997741 0.87 PPARG (0.55) PPARGPPARDPPARAMMP9SMN1; SMN2
SCHEMBL19734616 0.85 NPC1 (0.57) PPARGPPARDPPARAF2F10
SCHEMBL15966172 0.84 PPARG (0.51) PPARGPPARDPPARAMMP9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10287226-B2 Mild catalytic reduction of C—O bonds and C═O bonds using a recyclable catalyst system ORGANOFUEL SWEDEN AB (SE) 2019-05-14 US disclosed
US-20170334819-A1 A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM ORGANOFUEL SWEDEN AB (SE) 2017-11-23 US disclosed
US-20170334819-A1 A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM ORGANOFUEL SWEDEN AB (SE) 2017-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334819-A1 A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM CBR1, ADH1C, AOC2 PPARG 3080/4885PPARD 4294/4885PPARA 2411/4885
US-10287226-B2 Mild catalytic reduction of C—O bonds and C═O bonds using a recyclable catalyst system CBR1, ADH1C, CBR3 PPARG 2926/4885PPARD 4065/4885PPARA 2284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.