SCHEMBL19632845

SCHEMBL19632845

COc1ccccc1OC(CO)C(O)c1cc(OC)c(OCc2ccccc2)c(OC)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
MMP9 P14780 1/20 0.42
KDM4E B2RXH2 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
AGTR1 P30556 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.41
HTR1A P08908 2/20 0.40
ADRA1D P25100 2/20 0.40
ADRA1A P35348 2/20 0.40
ADRA1B P35368 2/20 0.40
RXRA P19793 1/20 0.40
BCHE P06276 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19628278 0.93 MMP9 (0.39) MGAMGAASIMGAM2MMP9
SCHEMBL19628282 0.87 PPARG (0.51) GAAMMP9KDM4EMEN1KMT2A
SCHEMBL15954804 0.86 MMP9 (0.50) MMP9L3MBTL1MEN1KMT2AAGTR1
SCHEMBL19632601 0.83 SLC6A5 (0.43) MMP9L3MBTL1AGTR1LMNACYP1A2
SCHEMBL15965419 0.83 MMP9 (0.44) MMP9KDM4EL3MBTL1KMT2ATDP1
SCHEMBL15965417 0.81 MMP9 (0.47) MMP9L3MBTL1KMT2AAGTR1LMNA
SCHEMBL13499773 0.81 MMP9 (0.50) GAAMMP9KDM4EKMT2AAGTR1
SCHEMBL1081415 0.80 CYP1A2 (0.49) MMP9MEN1KMT2AAGTR1LMNA
SCHEMBL9579548 0.79 PPARG (0.63) GAAMMP9KMT2AAGTR1LMNA
SCHEMBL22833918 0.79 PPARG (0.63) GAAMMP9KMT2AAGTR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10287226-B2 Mild catalytic reduction of C—O bonds and C═O bonds using a recyclable catalyst system ORGANOFUEL SWEDEN AB (SE) 2019-05-14 US disclosed
US-20170334819-A1 A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM ORGANOFUEL SWEDEN AB (SE) 2017-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334819-A1 A MILD CATALYTIC REDUCTION OF C-O BONDS AND C=O BONDS USING A RECYCLABLE CATALYST SYSTEM CBR1, ADH1C, AOC2 MGAM 220/4885GAA 1025/4885SI 838/4885
US-10287226-B2 Mild catalytic reduction of C—O bonds and C═O bonds using a recyclable catalyst system CBR1, ADH1C, CBR3 MGAM 179/4885GAA 1047/4885SI 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.