Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11990712 | 1.00 | TAAR1 (0.56) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL19628486 | 0.88 | TAAR1 (0.52) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL8512221 | 0.86 | TAAR1 (0.50) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL21242301 | 0.84 | TAAR1 (0.48) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL23934035 | 0.83 | TAAR1 (0.47) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL2736624 | 0.82 | TAAR1 (0.60) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL21755872 | 0.82 | TAAR1 (0.60) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL681082 | 0.82 | TAAR1 (0.60) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL7558271 | 0.81 | TAAR1 (0.46) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL4785594 | 0.81 | SIGMAR1 (0.64) | TAAR1SIGMAR1SLC6A2CYP2A6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9056396-A | — | — | None | — | — | JP | disclosed |
| US-20230233560-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-07-27 | — | — | US | disclosed |
| WO-2010018867-A1 | DI-SUBSTITUTED BENZOPYRANE COMPOUND | 日産化学工業株式会社 (JP) | 2010-02-18 | — | — | WO | disclosed |
| EP-0579284-B1 | Novel epoxy resins and electrostatographic toner containing the same as a binder | MITSUI CHEMICALS INC (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0336724-B1 | Process for preparing polyol resins | MITSUI PETROCHEMICAL IND (JP) | 1997-10-01 | — | — | EP | disclosed |
| JP-H0956396-A | PRODUCTION OF OPTICALLY ACTIVE 3-METHYL-2-PHENYLBUTYLAMINE | NAGASE & CO LTD | 1997-03-04 | — | — | JP | disclosed |
| US-5401436-A | Liquid crystal | ASAHI DENKA KOGKO KABUSHIKI KAISHA (JP) | 1995-03-28 | — | — | US | disclosed |
| CN-1025341-C | Preparation method of epoxy resin | MITSUI PETROCHEMICAL IND CO (JP) | 1994-07-06 | — | — | CN | disclosed |
| EP-0579284-A2 | Novel epoxy resins and electrostatographic toner containing the same as a binder | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5268435-A | Modifying a bisphenol epoxy resin | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-07 | — | — | US | disclosed |
| EP-0107492-B1 | HELICHROMIC-SMECTIC LIQUID CRYSTAL COMPOSITIONS AND DISPLAY CELLS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| CN-1034555-A | Neo-epoxy resin and with its electrostatographic toner containing as caking agent | MITSUI PETROCHEMICAL IND (JP) | 1989-08-09 | — | — | CN | disclosed |
| EP-0317367-A2 | Epoxy resins and electrostatographic toner containing the same as binder | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-24 | — | — | EP | disclosed |
| EP-0211600-A2 | Polyol resins and coating compositions containing same | MITSUI SEKIYU KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-02-25 | — | — | EP | disclosed |
| EP-0044666-B1 | HELICHROMIC COMPOUNDS AND DISPLAYS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-05-29 | — | — | EP | disclosed |
| US-4514045-A | DICHROISM; COMPLETE LIGHT ABSORPTION; LOW VOLTAGE; CONTRAST | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0107492-A2 | Helichromic-smectic liquid crystal compositions and display cells | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4394070-A | Helichromic compounds and displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0044666-A2 | Helichromic compounds and displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-01-27 | — | — | EP | disclosed |
| JP-H00956396-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233560-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | TAAR1 2181/4885SIGMAR1 764/4885SLC6A2 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.