Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439820 | 0.84 | MEN1 (0.50) | TRPV1LPAR1LPAR2LPAR3EPHX2 | |
| SCHEMBL818049 | 0.84 | MEN1 (0.50) | TRPV1LPAR1LPAR2LPAR3EPHX2 | |
| SCHEMBL20143663 | 0.83 | DNM1 (0.44) | LPAR1LPAR2LPAR3EPHX2 | |
| SCHEMBL10066198 | 0.83 | SLC6A5 (0.38) | FAAHTRPV1LPAR1LPAR2LPAR3 | |
| SCHEMBL10065902 | 0.83 | SLC6A5 (0.38) | FAAHTRPV1LPAR1LPAR2LPAR3 | |
| SCHEMBL12458461 | 0.83 | SLC6A5 (0.38) | FAAHTRPV1LPAR1LPAR2LPAR3 | |
| SCHEMBL13679072 | 0.83 | SLC6A5 (0.38) | FAAHTRPV1LPAR1LPAR2LPAR3 | |
| SCHEMBL14597545 | 0.81 | SLC6A5 (0.38) | FAAHTRPV1LPAR1LPAR2LPAR3 | |
| SCHEMBL5526732 | 0.81 | DNM1 (0.46) | LPAR1LPAR2LPAR3EPHX2 | |
| SCHEMBL10065906 | 0.81 | MEN1 (0.43) | TRPV1LPAR1LPAR2LPAR3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201342-A1 | POLYNUCLEOTIDES ENCODING JAGGED1 FOR THE TREATMENT OF ALAGILLE SYNDROME | MODERNATX, INC. (US) | 2017-11-23 | — | — | WO | disclosed |