SCHEMBL19630103

SCHEMBL19630103

C=Cc1c(F)ccc2c1N(CC)C(=O)C2

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.36
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
PTGER3 P43115 3/20 0.32
BMPR1B O00238 1/20 0.31
BMPR1A P36894 1/20 0.31
TGFBR1 P36897 1/20 0.31
ACVRL1 P37023 1/20 0.31
ACVR1 Q04771 1/20 0.31
ATAD2 Q6PL18 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19616460 0.88 BRD4 (0.36) BRD4ALDH1A1GAAPTGER3BMPR1B
SCHEMBL19629951 0.82 BMPR1B (0.37) BMPR1BBMPR1ATGFBR1ACVRL1ACVR1
SCHEMBL19630004 0.79 BRD4 (0.35) BRD4ALDH1A1GAABMPR1BBMPR1A
SCHEMBL5001527 0.75 CHRM1 (0.39) BRD4ALDH1A1GAAPTGER3BMPR1B
SCHEMBL19615468 0.68 BMPR1B (0.38) ALDH1A1GAABMPR1BBMPR1ATGFBR1
SCHEMBL4997606 0.68 ATAD2 (0.44) BRD4ALDH1A1GAABMPR1BBMPR1A
SCHEMBL31528058 0.67 HSP90B1 (0.35)
SCHEMBL5506028 0.66 CHRM5 (0.48) ALDH1A1GAA
SCHEMBL11631002 0.66 L3MBTL1 (0.40) ALDH1A1GAA
SCHEMBL10743515 0.66 ALDH1A1 (0.41) BRD4ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458452-B1 HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION BUGWORKS RES INC (US) 2023-08-30 EP disclosed
US-10711011-B2 Substituted oxazolidines as anti-bacterial agents Bugworks Research, Inc. (US) 2020-07-14 US disclosed
US-20190292199-A1 HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION Bugworks Research, Inc. 2019-09-26 US disclosed
WO-2017199265-A1 HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION BUGWORKS RESEARCH INDIA PVT LTD (IN) 2017-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292199-A1 HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION ALPI, UROD, HLA-C BRD4 4486/4885ALDH1A1 1285/4885GAA 127/4885
US-10711011-B2 Substituted oxazolidines as anti-bacterial agents ALPI, HLA-A, HLA-B BRD4 4649/4885ALDH1A1 568/4885GAA 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.