SCHEMBL599252

SCHEMBL599252

Oc1ccc(-n2cccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VHL P40337 1/20 0.56
ELOC Q15369 1/20 0.56
ELOB Q15370 1/20 0.56
ENPP2 Q13822 1/20 0.52
MKNK1 Q9BUB5 1/20 0.52
MKNK2 Q9HBH9 1/20 0.52
KDM4E B2RXH2 3/20 0.50
GAA P10253 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
POLB P06746 4/20 0.48
NSD2 O96028 1/20 0.48
GRK2 P25098 1/20 0.48
CASP6 P55212 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
AOC2 O75106 2/20 0.47
ALDH1A1 P00352 5/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20649339 0.77 KMT2A (0.59) VHLELOCELOBENPP2MKNK1
SCHEMBL44284 0.73 KDM4E (0.50) VHLELOCELOBKDM4EGAA
SCHEMBL1366622 0.72 L3MBTL1 (0.56) VHLELOCELOBKDM4EGAA
SCHEMBL393880 0.72 KDM4E (0.50) VHLELOCELOBKDM4EGAA
SCHEMBL2239811 0.72 ALDH1A1 (0.56) VHLELOCELOBKDM4EGAA
SCHEMBL296099 0.72 MAPT (0.56) VHLELOCELOBKDM4EGAA
SCHEMBL196307 0.72 NOTUM (0.52) VHLELOCELOBKDM4EGAA
SCHEMBL5547132 0.72 KDM4E (0.50) VHLELOCELOBKDM4EGAA
SCHEMBL11822364 0.72 KDM4E (0.50) VHLELOCELOBKDM4EGAA
SCHEMBL29201170 0.72 MEN1 (0.43) ENPP2MKNK1MKNK2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015183931-A1 STABILIZED CHEMILUMINESCENT SYSTEM LI-COR, INC. (US) 2015-12-03 WO claimed
US-20150346202-A1 STABILIZED CHEMILUMINESCENT SYSTEM Ll-COR, INC. (US) 2015-12-03 US claimed
EP-4689159-A1 METHOD AND KITS Oxford Nanopore Technologies PLC (GB) 2026-02-11 EP disclosed
US-12391781-B2 Black particles, black coating material, coating film, and black matrix for color filters SEKISUI CHEMICAL CO., LTD. (JP) 2025-08-19 US disclosed
EP-4063426-B1 BLACK PARTICLES, BLACK COATING MATERIAL, COATING FILM, AND BLACK MATRIX FOR COLOR FILTERS SEKISUI CHEMICAL CO LTD (JP) 2025-06-18 EP disclosed
WO-2025070747-A1 METHOD FOR MEASURING ANTIGEN CONTAINED IN TEST SAMPLE, AND KIT FOR MEASURING HUMAN CHORIONIC GONADOTROPIN OR ESTRADIOL 富士フイルム株式会社 2025-04-03 WO disclosed
EP-4526468-A1 METHOD AND ADAPTORS Oxford Nanopore Technologies PLC (GB) 2025-03-26 EP disclosed
WO-2024200280-A1 METHOD AND KITS OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-10-03 WO disclosed
WO-2023222657-A1 METHOD AND ADAPTORS OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-11-23 WO disclosed
CN-114502677-B Black particles, black paint, coating film, and black matrix for color filter 积水化学工业株式会社 2023-11-14 CN disclosed
CN-116466091-A Kit for detecting IgA immune complex based on chemiluminescence method 深圳市陆为生物技术有限公司 2023-07-21 CN disclosed
WO-2003051841-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
WO-2003051842-A2 COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
EP-1311482-A2 NON-IMIDAZOLE ARYLOXYPIPERIDINES AS H3 RECEPTOR LIGANDS Ortho-McNeil Pharmaceutical, Inc. (US) 2003-05-21 EP disclosed
WO-2002044120-A1 COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR III KARO BIO AB (SE) 2002-06-06 WO disclosed
US-20020040024-A1 Non-imidazole aryloxypiperidines NORTEL NETWORKS LIMITED (CA) 2002-04-04 US disclosed
WO-2002012190-A2 NON-IMIDAZOLE ARYLOXYPIPERIDINES AS H3 RECEPTOR LIGANDS ORTHO MCNEIL PHARMACEUTICAL, INC. (US) 2002-02-14 WO disclosed
US-4072754-A ANTICHOLESTEROL MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-02-07 US disclosed
US-4016283-A ADRENERGIC BLOCKING AGENTS CIBA-GEIGY CORPORATION (US) 1977-04-05 US disclosed
US-3984436-A BLOCKERS OF ADRENERGIC B-RECEPTORS CIBA-GEIGY CORPORATION (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040024-A1 Non-imidazole aryloxypiperidines HRH2, HRH4, HRH3 VHL 1737/4885ELOC 3911/4885ELOB 3761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.