SCHEMBL296099

SCHEMBL296099

Nc1ccc(-n2cccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
LMNA P02545 2/20 0.52
KDM4E B2RXH2 4/20 0.50
GAA P10253 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
VHL P40337 1/20 0.50
ELOC Q15369 1/20 0.50
ELOB Q15370 1/20 0.50
AOC2 O75106 2/20 0.47
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
ALDH1A1 P00352 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HTT P42858 2/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 3/20 0.43
NSD2 O96028 1/20 0.43
GRK2 P25098 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7128290 0.93 CYP3A4 (0.52) MAPTLMNAKDM4EGAANPSR1
SCHEMBL20253478 0.87 ALDH1A1 (0.58) MAPTLMNAKDM4EGAANPSR1
SCHEMBL78611 0.77 KMT2A (0.53) MAPTLMNAKDM4EGAANPSR1
SCHEMBL44284 0.73 KDM4E (0.50) MAPTKDM4EGAANPSR1L3MBTL1
SCHEMBL599252 0.72 VHL (0.56) MAPTLMNAKDM4EGAANPSR1
SCHEMBL5547132 0.72 KDM4E (0.50) MAPTLMNAKDM4EGAANPSR1
SCHEMBL11822364 0.72 KDM4E (0.50) MAPTKDM4EGAANPSR1L3MBTL1
SCHEMBL393880 0.72 KDM4E (0.50) MAPTKDM4EGAANPSR1L3MBTL1
SCHEMBL196307 0.72 NOTUM (0.52) MAPTLMNAKDM4EGAANPSR1
SCHEMBL1260035 0.72 KDM4E (0.50) MAPTLMNAKDM4EGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117542666-A Porous ordered graphene/polypyrrole covalent composite supercapacitor electrode material and preparation method and application thereof 华南理工大学 2024-02-09 CN claimed
CN-110790535-B Maintenance method of asphalt road 广东高翔建设有限公司 2021-07-06 CN claimed
CN-110105336-B Viologen derivative electrochromic material and preparation method thereof 华南理工大学 2020-09-22 CN claimed
US-10566106-B2 Conjugated polymer coatings and methods for atmospheric plasma deposition thereof THE BOEING COMPANY (US) 2020-02-18 US claimed
CN-110790535-A Maintenance method of asphalt road 广东高翔建设有限公司 2020-02-14 CN claimed
CN-110105336-A Viologen derivative electrochromic material and preparation method thereof 华南理工大学 2019-08-09 CN claimed
US-20160049226-A1 CONJUGATED POLYMER COATINGS AND METHODS FOR ATMOSPHERIC PLASMA DEPOSITION THEREOF THE BOEING COMPANY 2016-02-18 US claimed
US-20080207694-A1 Hydroxamates as Histone Deacetylase Inhibitors and Pharmaceutical Formulations Containing Them ROSSI CRISTINA 2008-08-28 US claimed
EP-1868997-A1 HYDROXAMATES AS HISTONE DEACETYLASE INHIBITORS AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM Menarini International Operations Luxembourg S.A. (LU) 2007-12-26 EP claimed
WO-2006097460-A1 HYDROXAMATES AS HISTONE DEACETYLASE INHIBITORS AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A. (LU) 2006-09-21 WO claimed
CN-85106344-A Use contains the imaging system of the photosensitive microcapsules of 4-(4 '-aminophenyl)-pyridine compounds 1987-02-18 CN claimed
US-12391781-B2 Black particles, black coating material, coating film, and black matrix for color filters SEKISUI CHEMICAL CO., LTD. (JP) 2025-08-19 US disclosed
CN-120398828-A Red light delayed fluorescent material based on naphthalimide, and preparation method and application thereof 大连理工大学 2025-08-01 CN disclosed
EP-4063426-B1 BLACK PARTICLES, BLACK COATING MATERIAL, COATING FILM, AND BLACK MATRIX FOR COLOR FILTERS SEKISUI CHEMICAL CO LTD (JP) 2025-06-18 EP disclosed
CN-120081789-A Pyrazole derivative with antitumor activity and preparation method and application thereof 天津匠新致成科技有限公司 2025-06-03 CN disclosed
EP-1080092-A2 BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION WARNER-LAMBERT COMPANY (US) 2001-03-07 EP disclosed
WO-2001005393-A2 METHOD FOR TREATING CHRONIC PAIN USING MEK INHIBITORS WARNER-LAMBERT COMPANY (US) 2001-01-25 WO disclosed
WO-2000041505-A2 ANTHRANILIC ACID DERIVATIVES WARNER-LAMBERT COMPANY (US) 2000-07-20 WO disclosed
WO-1999061444-A2 BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION WARNER-LAMBERT COMPANY (US) 1999-12-02 WO disclosed
US-4617316-A Insecticidal heteroaryl substituted phenyl benzoylureas FMC CORPORATION (US) 1986-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207694-A1 Hydroxamates as Histone Deacetylase Inhibitors and Pharmaceutical Formulations Containing Them HDAC1, HDAC8, HDAC9 MAPT 791/4885LMNA 1681/4885KDM4E 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.