Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.50 |
| ▸ | NOS2 | P35228 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773469 | 0.77 | PI4KA (0.59) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL8773467 | 0.77 | PI4KA (0.59) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL4684501 | 0.75 | RAB9A (0.56) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL1677741 | 0.74 | NOS3 (0.68) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL9223659 | 0.71 | L3MBTL1 (0.50) | RAB9AMAPTGFERL3MBTL1ALDH1A1 | |
| SCHEMBL2275595 | 0.71 | RAB9A (0.56) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL29646253 | 0.71 | PIK3CA (0.82) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL334946 | 0.71 | RAB9A (0.66) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL5532470 | 0.71 | PIK3CA (0.82) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL28208524 | 0.71 | NOS3 (0.50) | RAB9AMAPTHTTAXLGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201155-A1 | lSOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2017-11-23 | — | — | WO | disclosed |