Tefluthrin

Tefluthrin

SCHEMBL1963314

Cc1c(F)c(F)c(COC(=O)[C@@H]2[C@H](C=C(Cl)C(F)(F)F)C2(C)C)c(F)c1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
LMNA P02545 3/20 0.42
ATM Q13315 2/20 0.42
ADRA2A P08913 1/20 0.42
CNR1 P21554 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tefluthrin SCHEMBL20823 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL16536934 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL2740810 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL14427331 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL4622567 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL4622566 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL1920781 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL8769136 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL1898396 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL21112033 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008085363-A1 COMBINATION LIGHT DEVICE WITH INSECT CONTROL INGREDIENT EMISSION S. C. JOHNSON & SON, INC. (US) 2008-07-17 WO claimed
US-20080113940-A1 Insecticidal Compositions ERDELEN CHRISTOPH 2008-05-15 US claimed
EP-1649750-A2 Synergistic insecticidal mixtures based on chloronicotinyl insecticides Bayer CropScience AG (DE) 2006-04-26 EP claimed
US-20020193352-A1 Insecticides ERDELEN CHRISTOPH (DE) 2002-12-19 US claimed
US-20010025050-A1 Insecticidal compositions ERDELEN CHRISTOPH (DE) 2001-09-27 US claimed
US-6218407-B1 Insecticides BAYER AKTIENGESELLSCHAFT (DE) 2001-04-17 US claimed
EP-0828421-A1 INSECTICIDES BAYER AG (DE) 1998-03-18 EP claimed
WO-1996037105-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-28 WO claimed
US-6444690-B1 None US disclosed
WO-2015028034-A1 COMBINATION OF 2,3,5,6-TETRAFLUORO-4-METHYLBENZYL (Z)-(1 R)-CIS-3-(2-CHLORO-3,3,3-TRIFLUORO-1 -PROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE WITH AT LEAST ONE INSECTICIDE, ACARICIDE, NEMATICIDE AND/OR FUNGICIDE. CHEMINOVA A/S (DK) 2015-03-05 WO disclosed
WO-2015028034-A1 COMBINATION OF 2,3,5,6-TETRAFLUORO-4-METHYLBENZYL (Z)-(1 R)-CIS-3-(2-CHLORO-3,3,3-TRIFLUORO-1 -PROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE WITH AT LEAST ONE INSECTICIDE, ACARICIDE, NEMATICIDE AND/OR FUNGICIDE. CHEMINOVA A/S (DK) 2015-03-05 WO disclosed
US-20110144058-A1 INSECTICIDAL COMPOSITIONS BAYER CROPSCIENCE AG (DE) 2011-06-16 US disclosed
US-7445791-B2 Synergistic insecticidal composition containing Chloronicotynyle and Organosphosphorus compounds UNITED PHOSPHORUS, LTD. (IN) 2008-11-04 US disclosed
US-20080113940-A1 Insecticidal Compositions ERDELEN CHRISTOPH 2008-05-15 US disclosed
US-20020193352-A1 Insecticides ERDELEN CHRISTOPH (DE) 2002-12-19 US disclosed
US-6444690-B2 INSECTICIDAL MIXTURES OF CHLORONICOTINYL INSECTICIDES WITH ONE OR MORE SYNERGISTS FROM THE GROUP AZINPHOS-METHYL, CURACRON, MESUROL, CHLORFENAPYR, TAMARON, ABAMECTIN, TRIAZURON, ENDOSULFAN, HEXYTHIAZOX, METHIOCARB AND OTHERS BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 US disclosed
US-20010025050-A1 Insecticidal compositions ERDELEN CHRISTOPH (DE) 2001-09-27 US disclosed
US-6225495-B1 PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-01 US disclosed
US-6060489-A SYNERGISTIC MIXTURE COMPRISING IMIDACLOPRID AND MESUROL; ARACHNIDS, NEMATODES BAYER AKTIENGESELLSCHAFT (DE) 2000-05-09 US disclosed
US-5994331-A SYNERGISTIC MIXTURE BAYER ATIENGESELLSCHAFT (DE) 1999-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113940-A1 Insecticidal Compositions CBR3, CBR1, CNPY3 TDP1 4395/4885MEN1 2348/4885KMT2A 2488/4885
US-20020193352-A1 Insecticides CBR1, CBR3, CLIC1 TDP1 2886/4885MEN1 2524/4885KMT2A 2043/4885
US-20110144058-A1 INSECTICIDAL COMPOSITIONS CBR3, CBR1, CNPY3 TDP1 4414/4885MEN1 2210/4885KMT2A 2602/4885
US-20010025050-A1 Insecticidal compositions CBR3, CBR1, CYCS TDP1 3812/4885MEN1 3242/4885KMT2A 2542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.