Tefluthrin

Tefluthrin

SCHEMBL1920781

Cc1c(F)c(F)c(COC(=O)C2C(C=C(Cl)C(F)(F)F)C2(C)C)c(F)c1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
LMNA P02545 3/20 0.42
ATM Q13315 2/20 0.42
ADRA2A P08913 1/20 0.42
CNR1 P21554 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tefluthrin SCHEMBL20823 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL16536934 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL2740810 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL14427331 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL4622567 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL4622566 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL8769136 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL1898396 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL21112033 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM
Tefluthrin SCHEMBL1963314 1.00 TDP1 (1.00) TDP1MEN1KMT2ALMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3014994-B1 MICROCAPSULES FOR THERMAL TRANSPIRATION SUMITOMO CHEMICAL CO (JP) 2019-11-20 EP claimed
US-20160192644-A1 MICROCAPSULES FOR THERMAL TRANSPIRATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-07 US claimed
EP-3014994-A1 MICROCAPSULES FOR THERMAL TRANSPIRATION Sumitomo Chemical Co., Ltd (JP) 2016-05-04 EP claimed
WO-2015028034-A1 COMBINATION OF 2,3,5,6-TETRAFLUORO-4-METHYLBENZYL (Z)-(1 R)-CIS-3-(2-CHLORO-3,3,3-TRIFLUORO-1 -PROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE WITH AT LEAST ONE INSECTICIDE, ACARICIDE, NEMATICIDE AND/OR FUNGICIDE. CHEMINOVA A/S (DK) 2015-03-05 WO claimed
EP-0538246-A1 PYRETHROID FORMULATIONS OF REDUCED PARESTHESIA. ICI AMERICA INC (US) 1993-04-28 EP claimed
WO-1990008467-A1 PYRETHROID FORMULATIONS OF REDUCED PARESTHESIA ICI AMERICAS INC. (US) 1990-08-09 WO claimed
EP-3014994-B1 MICROCAPSULES FOR THERMAL TRANSPIRATION SUMITOMO CHEMICAL CO (JP) 2019-11-20 EP disclosed
US-20160192644-A1 MICROCAPSULES FOR THERMAL TRANSPIRATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-07 US disclosed
EP-3014994-A1 MICROCAPSULES FOR THERMAL TRANSPIRATION Sumitomo Chemical Co., Ltd (JP) 2016-05-04 EP disclosed
WO-2015028034-A1 COMBINATION OF 2,3,5,6-TETRAFLUORO-4-METHYLBENZYL (Z)-(1 R)-CIS-3-(2-CHLORO-3,3,3-TRIFLUORO-1 -PROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATE WITH AT LEAST ONE INSECTICIDE, ACARICIDE, NEMATICIDE AND/OR FUNGICIDE. CHEMINOVA A/S (DK) 2015-03-05 WO disclosed
EP-2685830-A1 PEST CONTROL COMPOSITION AND PEST CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2014-01-22 EP disclosed
WO-2012124796-A1 PEST CONTROL COMPOSITION AND PEST CONTROL METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-20 WO disclosed
EP-2034840-B1 PESTICIDAL COMPOSITION COMPRISING TETRAFLUOROBENZYL CYCLOPROPANE CARBOXYLATES SUMITOMO CHEMICAL CO (JP) 2011-06-01 EP disclosed
EP-0498396-A2 N-phenylcarbamate compound, process for preparing the same and biocidal composition for control of harmful organisms ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-08-12 EP disclosed
EP-0483647-A1 Hydrazine compounds or their salts, processes for producing them and pesticides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1992-05-06 EP disclosed
WO-1990008467-A1 PYRETHROID FORMULATIONS OF REDUCED PARESTHESIA ICI AMERICAS INC. (US) 1990-08-09 WO disclosed
EP-0206318-B1 ORGANOPHOSPHORUS COMPOUNDS, PROCESS FOR THEIR PREPARATION AND INSECTICIDAL, MITICIDAL, NEMATICIDAL OR SOIL PESTICIDAL COMPOSITIONS CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 1990-04-11 EP disclosed
EP-0349999-A2 Process for preparing highly active water-dispersible pesticides DOWELANCO (US) 1990-01-10 EP disclosed
US-4783451-A Organophosphorus, compounds and insecticidal, miticidal, nematicidal or soil pesticidal compositions containing them ISHIHARA SANGYO KAISHA LTD. (JP) 1988-11-08 US disclosed
US-4645761-A Organophosphorus compounds and insecticidal, miticidal, nematicidal or soil pesticidal compositions containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1987-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160192644-A1 MICROCAPSULES FOR THERMAL TRANSPIRATION TERT, METTL3, TRHDE TDP1 3311/4885MEN1 985/4885KMT2A 746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.