Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | GAK | O14976 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.47 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633574 | 0.91 | CTSV (0.56) | KMT2ALMNAMITFABCG2CTSV | |
| SCHEMBL19633575 | 0.91 | CTSV (0.49) | KMT2ALMNAMITFABCG2CTSV | |
| SCHEMBL19633656 | 0.90 | AKR1C3 (0.58) | KMT2ALMNAMITFAKR1C3AKR1C2 | |
| SCHEMBL19633777 | 0.90 | GAK (0.57) | KMT2ALMNAMITFAKR1C3AKR1C2 | |
| SCHEMBL19633684 | 0.86 | KMT2A (0.64) | KMT2ALMNAMITFAKR1C3AKR1C2 | |
| SCHEMBL19633519 | 0.86 | GAK (0.57) | GAKRIPK2COQ8ANLKPTK6 | |
| SCHEMBL19633549 | 0.84 | KMT2A (0.55) | KMT2ALMNAMITFAKR1C3AKR1C2 | |
| SCHEMBL19633569 | 0.82 | KMT2A (0.52) | KMT2ALMNAMITFAKR1C3AKR1C2 | |
| SCHEMBL19633621 | 0.82 | KMT2A (0.49) | KMT2ALMNAMITFAKR1C3AKR1C2 | |
| SCHEMBL19633806 | 0.81 | KMT2A (0.51) | KMT2ALMNAMITFAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |