Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.56 |
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | PTK6 | Q13882 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633575 | 0.91 | CTSV (0.49) | CTSVCTSLKMT2ALMNAMITF | |
| SCHEMBL19633573 | 0.91 | KMT2A (0.49) | CTSVCTSLKMT2ALMNAMITF | |
| SCHEMBL19633545 | 0.89 | KMT2A (0.49) | CTSVCTSLKMT2ALMNAMITF | |
| SCHEMBL19633777 | 0.87 | GAK (0.57) | KMT2ALMNAMITFPTK6ALDH1A1 | |
| SCHEMBL19633684 | 0.87 | KMT2A (0.64) | KMT2ALMNAMITFPTK6MAPT | |
| SCHEMBL19633549 | 0.85 | KMT2A (0.55) | KMT2ALMNAMITFPTK6MAPT | |
| SCHEMBL19633656 | 0.84 | AKR1C3 (0.58) | KMT2ALMNAMITFPTK6ERBB2 | |
| SCHEMBL19633621 | 0.84 | KMT2A (0.49) | KMT2ALMNAMITFPTK6MEN1 | |
| SCHEMBL19633569 | 0.82 | KMT2A (0.52) | KMT2ALMNAMITFPTK6MAPT | |
| SCHEMBL19633508 | 0.82 | PTK6 (0.53) | CTSVCTSLKMT2APTK6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |