Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ARNT | P27540 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633549 | 0.92 | KMT2A (0.55) | KMT2AMITFLMNAMEN1PTK6 | |
| SCHEMBL19633656 | 0.89 | AKR1C3 (0.58) | KMT2AMITFLMNAPTK6ERBB2 | |
| SCHEMBL19633569 | 0.89 | KMT2A (0.52) | KMT2AMITFLMNAMEN1PTK6 | |
| SCHEMBL19633574 | 0.87 | CTSV (0.56) | KMT2AMITFLMNAMEN1PTK6 | |
| SCHEMBL19633621 | 0.87 | KMT2A (0.49) | KMT2AMITFLMNAMEN1PTK6 | |
| SCHEMBL19633806 | 0.86 | KMT2A (0.51) | KMT2AMITFLMNAMEN1PTK6 | |
| SCHEMBL19633573 | 0.86 | KMT2A (0.49) | KMT2AMITFLMNAMEN1PTK6 | |
| SCHEMBL19633545 | 0.84 | KMT2A (0.49) | KMT2AMITFLMNAMEN1PTK6 | |
| SCHEMBL19633575 | 0.84 | CTSV (0.49) | KMT2AMITFLMNAMEN1PTK6 | |
| SCHEMBL19633777 | 0.84 | GAK (0.57) | KMT2AMITFLMNAPTK6ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |