Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 4/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.43 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.43 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.40 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.40 |
| ▸ | TXK | P42681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633682 | 0.92 | GSK3A (0.52) | GAKCCNCCDK8GSK3AGSK3B | |
| SCHEMBL19633681 | 0.92 | CCNC (0.51) | GAKCCNCCDK8GSK3AGSK3B | |
| SCHEMBL19633566 | 0.82 | SIRT2 (0.47) | GAKALKERBB2SIRT2KDR | |
| SCHEMBL19633687 | 0.82 | ERBB2 (0.49) | GAKRIPK2COQ8ANLKALK | |
| SCHEMBL19633503 | 0.80 | GAK (0.53) | GAKGSK3AGSK3BRIPK2COQ8A | |
| SCHEMBL19633692 | 0.78 | CCNC (0.50) | CCNCCDK8ALKERBB2HRH3 | |
| SCHEMBL19633545 | 0.77 | KMT2A (0.49) | CCNCCDK8ALKERBB2KDM4E | |
| SCHEMBL19633778 | 0.76 | GAK (0.69) | GAKGSK3AGSK3BRIPK2COQ8A | |
| SCHEMBL27969044 | 0.73 | MAOA (0.50) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL29200458 | 0.72 | GAK (0.64) | GAKCCNCCDK8GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |