Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633545 | 0.90 | KMT2A (0.49) | CCNCCDK8KMT2APOLBERBB2 | |
| SCHEMBL19633643 | 0.85 | MAPT (0.49) | CCNCCDK8KMT2APOLBCYP19A1 | |
| SCHEMBL19633815 | 0.85 | MEN1 (0.51) | CCNCCDK8KMT2APOLBCYP19A1 | |
| SCHEMBL19633687 | 0.85 | ERBB2 (0.49) | KMT2APOLBERBB2HRH3ALK | |
| SCHEMBL19633681 | 0.82 | CCNC (0.51) | CCNCCDK8ERBB2HRH3ALK | |
| SCHEMBL19633574 | 0.79 | CTSV (0.56) | CCNCCDK8KMT2APOLBERBB2 | |
| SCHEMBL19633566 | 0.79 | SIRT2 (0.47) | ERBB2ALKEGFRSIRT2 | |
| SCHEMBL19633690 | 0.78 | GAK (0.47) | CCNCCDK8KMT2APOLBERBB2 | |
| SCHEMBL19633503 | 0.78 | GAK (0.53) | ERBB2ALKEGFRHTTSIRT2 | |
| SCHEMBL19633549 | 0.78 | KMT2A (0.55) | KMT2APOLBERBB2EGFRMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |