Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 19/20 | 0.69 |
| ▸ | RIPK2 | O43353 | 11/20 | 0.65 |
| ▸ | COQ8A | Q8NI60 | 11/20 | 0.65 |
| ▸ | NLK | Q9UBE8 | 11/20 | 0.65 |
| ▸ | EPHB6 | O15197 | 3/20 | 0.60 |
| ▸ | ABL1 | P00519 | 3/20 | 0.60 |
| ▸ | LCK | P06239 | 2/20 | 0.60 |
| ▸ | EPHA1 | P21709 | 2/20 | 0.60 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.60 |
| ▸ | TXK | P42681 | 1/20 | 0.60 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.54 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.54 |
| ▸ | STK16 | O75716 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633751 | 0.92 | GAK (0.66) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633713 | 0.84 | GAK (0.49) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633780 | 0.82 | GAK (0.71) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633629 | 0.80 | GSK3A (0.61) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633698 | 0.77 | TUBB1 (0.57) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633777 | 0.77 | GAK (0.57) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633690 | 0.76 | GAK (0.47) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633749 | 0.75 | TUBB1 (0.54) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633779 | 0.75 | TUBB1 (0.65) | GAKRIPK2COQ8ANLKEPHB6 | |
| SCHEMBL19633699 | 0.73 | GAK (0.57) | GAKRIPK2COQ8ANLKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |