Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 2/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.49 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.49 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633759 | 0.91 | TUBB1 (0.49) | GAKRIPK2COQ8ANLKKDR | |
| SCHEMBL19633762 | 0.90 | TUBB1 (0.43) | GAKRIPK2COQ8ANLKKDR | |
| SCHEMBL19633648 | 0.90 | PDGFRA (0.46) | KDRPDGFRAABCB1CSF1RPDGFRB | |
| SCHEMBL19633520 | 0.89 | MAOB (0.46) | KDRPDGFRAHTR1AADRA1DADRA1A | |
| SCHEMBL19633760 | 0.85 | PDGFRA (0.48) | GAKRIPK2COQ8ANLKKDR | |
| SCHEMBL19633697 | 0.81 | GAK (0.53) | GAKRIPK2COQ8ANLKKDR | |
| SCHEMBL7487186 | 0.80 | KDR (0.58) | KDRPDGFRAPDGFRB | |
| SCHEMBL19633559 | 0.80 | KDR (0.42) | KDRPDGFRAHTR1AADRA1DADRA1A | |
| SCHEMBL19633683 | 0.79 | CYP3A4 (0.42) | KDRPDGFRAHTR1AADRA1DADRA1A | |
| SCHEMBL19633780 | 0.79 | GAK (0.71) | GAKRIPK2COQ8ANLKHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |