Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965256 | 0.79 | ACHE (0.49) | SIRT2SIRT1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL513344 | 0.76 | SIRT2 (0.40) | SIRT2SIRT1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14537170 | 0.74 | MAPK1 (0.56) | SIRT2SIRT1KMT2AMAPK1MAPT | |
| SCHEMBL1964598 | 0.73 | PTGS1 (0.39) | GRM5SMN1; SMN2TRPC5 | |
| SCHEMBL1964382 | 0.71 | PER2 (0.46) | SIRT2SIRT1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL514643 | 0.71 | SIRT2 (0.42) | SIRT2SIRT1TAS2R8 | |
| SCHEMBL4910875 | 0.70 | SIRT2 (0.39) | SIRT2SIRT1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7606492 | 0.69 | CHRM2 (0.37) | GRM5MAPT | |
| SCHEMBL6938726 | 0.68 | EPHX2 (0.42) | SIRT2SIRT1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14403257 | 0.68 | ALDH1A1 (0.67) | SIRT2SIRT1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102137841-B | Ortho-substituted haloalkylsulfonanilide derivative and herbicide | NISSAN CHEMICAL IND LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-102137841-A | Ortho-substituted haloalkylsulfonanilide derivative and herbicide | NISSAN CHEMICAL IND LTD | 2011-07-27 | — | — | CN | disclosed |
| EP-2336104-A1 | ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE | Nissan Chemical Industries, Ltd. (JP) | 2011-06-22 | — | — | EP | disclosed |