SCHEMBL1964382

SCHEMBL1964382

CC1CCN(Cc2ccccc2N)C(=O)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PER2 O15055 3/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
USP2 O75604 1/20 0.45
GAA P10253 1/20 0.45
SIRT2 Q8IXJ6 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
ACHE P22303 4/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CRY2 Q49AN0 1/20 0.38
TAS2R8 Q9NYW2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
MAPK1 P28482 1/20 0.35
P2RX7 Q99572 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13950136 0.84 ACHE (0.59) PER2KMT2AMEN1ACHEALDH1A1
SCHEMBL2578048 0.80 SIRT2 (0.41) KMT2AMEN1USP2GAASIRT2
SCHEMBL15014611 0.79 ACHE (0.56) PER2KMT2AACHENPC1RAB9A
SCHEMBL1964083 0.79 ACHE (0.66) PER2KMT2AMEN1SIRT2SIRT1
SCHEMBL14537170 0.74 MAPK1 (0.56) PER2KMT2ASIRT2SIRT1ACHE
SCHEMBL1966561 0.73 PTGS1 (0.39) PER2ACHENPC1RAB9ACRY2
SCHEMBL1963377 0.71 GRM5 (0.40) KMT2AMEN1SIRT2SIRT1TAS2R8
SCHEMBL514643 0.71 SIRT2 (0.42) PER2SIRT2SIRT1CRY2TAS2R8
SCHEMBL16371253 0.70 P2RX7 (0.38) PER2ALDH1A1CRY2TSHRP2RX7
SCHEMBL15228275 0.69 CHRM2 (0.45) PER2GAANPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102137841-B Ortho-substituted haloalkylsulfonanilide derivative and herbicide NISSAN CHEMICAL IND LTD 2014-05-14 CN disclosed
CN-102137841-A Ortho-substituted haloalkylsulfonanilide derivative and herbicide NISSAN CHEMICAL IND LTD 2011-07-27 CN disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed